Results 161 to 170 of about 1,339,441 (314)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Author Correction: Calcification in free‑living coralline algae is strongly influenced by morphology: Implications for susceptibility to ocean acidification

Scientific Reports, 2021
Nadine Schubert, Laurie C. Hofmann, Antonella C. Almeida Saá, Anderson Camargo Moreira, Rafael Güntzel Arenhart, Celso Peres Fernandes, Dirk de Beer, Paulo A. Horta, João Silva   +8 more
doaj   +1 more source

Microstructure, Mechanical Properties and Additive Manufacturing of Steels. [PDF]

Materials (Basel)
Bidulský R, Bidulská J.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Mechanical Properties of Biochar-Sulfur Composites. [PDF]

Materials (Basel)
Syguła E, Słupska M, Radziemska M, Białowiec A.   +3 more
europepmc   +1 more source

The influence of microporosity on the mechanical properties of bulk, scaffold, and composite scaffold biphasic calcium phosphate

, 2010
The mechanical properties of bulk microporous biphasic calcium phosphate (BCP), monolithic BCP scaffolds with multi-scale porosity (macro- and microporosity), and BCP/polymethylmethacrylate (PMMA) composite scaffolds with multi-scale porosity were ...
Herschler, Brad A.
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Forming Technologies and Mechanical Properties of Advanced Materials-Second Edition. [PDF]

Materials (Basel)
Trzepieciński T, Oleksik VŞ, Najm SM.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Impact of treated wastewater on the mechanical properties and durability of concrete. [PDF]

Sci Rep
Abdelazim O, Abdel-Latif I, Ismail S, Khalaf MA.   +3 more
europepmc   +1 more source