Results 241 to 250 of about 13,137,816 (371)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Investigation on Mechanical Properties of Functional Graded Hybrid TPMS Structures Inspired Bone Scaffolds. [PDF]

Polymers (Basel)
Karamanli İA.
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Key Factors Influencing the Mechanical Properties of Binodal Decomposed Metallic Glass Composites. [PDF]

Materials (Basel)
Wang Y, Zheng G, Li M.
europepmc   +1 more source

Effect of Martensite Structure and Carbide Precipitates on Mechanical Properties of Cr-Mo Alloy Steel with Different Cooling Rate

, 2018
Yaxu Zheng, Fuming Wang, Changrong Li, Yu Lin, Ruifang Cao   +4 more
openalex   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Effect of Rare Earth Elements (La and Ce) on Microstructure and Mechanical Properties of U75V Steel. [PDF]

Materials (Basel)
Hu M, Ren L, Feng G, Yang J, Liu Y.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Cellular mechanical properties in response to environmental viscosity imaged by Brillouin Microscopy. [PDF]

Commun Biol
Handler C, Zanini G, Smith IM, Stroka KM, Scarcelli G, Testi C.   +5 more
europepmc   +1 more source

Influence of Reaction-Induced Microphase-SeparationStructure on Mechanical Properties, Shape Memory, and Recyclable Performanceof EVA–Polyurea Nanocomposite

Niexin Li (9511064), Yong Wang (12837), Jiangan You (10141480), Zhiwei Jiang (139025), Yanhui Wang (108090), Haiping Xing (5428844), Minggang Li (5428841), Tao Tang (46868)   +7 more
openalex   +1 more source