Results 71 to 80 of about 3,065,991 (332)

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Detection of former goaf and analysis of deformation characteristics of overburden in Dameidong coal mine

open access: yesFrontiers in Earth Science, 2023
In order to analyze the deformation of the old goaf in Dameidong Coal Mine and its influence on the surrounding rock and soil layer, it provides guidance for the prevention and control of geological disasters in the region.
Zhan-Xi Wei   +9 more
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Sensors for mechanical properties

open access: yesJournal of Physics E: Scientific Instruments, 1983
This paper presents devices to convert a wide range of physical and mechanical properties into a displacement which can subsequently generate an instrumentation signal. The application of physical principles as the basis of a practical transducer is but one fascinating aspect of instrumentation.
openaire   +3 more sources

Transient electromagnetic detection and numerical simulation analysis of the deformation characteristics of an old goaf in an alpine coal mine area

open access: yesFrontiers in Earth Science, 2023
In this paper, Qinghai alpine mining area is taken as the research object to explore the deformation characteristics of overlying strata in alpine mining area, so as to prevent geological disasters caused by over-exploitation in alpine mining area.
Zhan-Xi Wei   +8 more
doaj   +1 more source

Comparison of Mechanical Properties of Austempered, Normalized and As-Weld Carbon Steel Weldment [PDF]

open access: yes, 2018
More often than not, welded joints experience failure such as fracture which jeopardize their reliability and ergonomics when put in perspective. Attempting a significant improvement in the mechanical properties of welded joint through heat treatment ...
Austine, O. (Okoro)   +2 more
core  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Mechanical and Nanomechanical Properties

open access: yes, 2007
The growing interest in nanomaterials over the past decade or so can be put down to their unique structure, characterised by grains with nanometric dimensions and by a rather high density of crystal defects, which will undoubtedly lead to quite exceptional properties. In particular, extrapolating the constitutive laws of large-grained materials down to
Tromas, Christophe   +7 more
openaire   +4 more sources

Mechanisms controlling the mechanical properties of the nuclei

open access: yesCurrent Opinion in Cell Biology, 2023
The mechanical properties of the nucleus influence different cellular and nuclear functions and have relevant implications for several human diseases. The nucleus protects genetic information while acting as a mechano-sensory hub in response to internal and external forces.
Bastianello G., Foiani M.
openaire   +2 more sources

Mechanical properties of Pt monatomic chains [PDF]

open access: yes, 2008
The mechanical properties of platinum monatomic chains were investigated by simultaneous measurement of an effective stiffness and the conductance using our newly developed mechanically controllable break junction (MCBJ) technique with a tuning fork as a
Mares, A. I.   +4 more
core   +3 more sources

Home - About - Disclaimer - Privacy