Results 71 to 80 of about 1,483,802 (353)

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Open string with a background B-field as the first order mechanics, noncommutativity and soldering formalism

, 2007
To study noncommutativity properties of the open string with constant B-field we construct a mechanical action which reproduces classical dynamics of the string sector under consideration.
A. A. Deriglazov, A. A. Deriglazov, C. Filgueiras, C. Neves, C. Wotzasek, D. M. Gitman, E. M. C. Abreu, E. M. C. Abreu, G. Dunne, J. Polchinski, L. Brink, M. B. Green, P. A. M. Dirac, S. Girvin, W. Oliveira   +14 more
core   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

Characterization of domestic high performance carbon fibers and mechanical properties of carbon fibers reinforced matrix composites

Cailiao gongcheng, 2020
The morphologies and surface chemical properties of domestic T800 grade carbon fibers A and imported Toray T800H were characterized by means of scanning electronic microscopy(SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS).
LI Guo-li, PENG Gong-qiu, ZHONG Xiang-yu
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Development of lightweight fire retardant, low-smoke, high-strength, thermally stable aircraft floor paneling [PDF]

Fire resistance mechanical property tests were conducted on sandwich configurations composed of resin-fiberglass laminates bonded with adhesives to Nomex honeycomb core.
Arnold, D. B., Burnside, J. V., Hajari, J. V.   +2 more
core   +4 more sources

Effect of Thermo-Oxidative, Ultraviolet and Ozone Aging on Mechanical Property Degradation of Carbon Black-Filled Rubber Materials

Buildings
Carbon black (CB)-filled rubber materials are extensively used in civil engineering seismic isolation. However, CB-filled rubber materials often experience mechanical property degradation because of exposure to environmental factors. To better understand
Bo Zhou, Wensong Liu, Youjian Huang, Jun Luo, Boyuan Yin   +4 more
doaj   +1 more source

Rapid multiple property determination from bulk materials libraries prepared from chemically synthesized powders

Scientific Reports, 2022
A variety of high-performance materials are utilized in electrical, electronic, and mechanical systems. Such systems account for a significant fraction of the world’s electricity consumption.
Li Ping Tan, V. Chaudhary, Z. Tsakadze, R. V. Ramanujan   +3 more
doaj   +1 more source