Results 81 to 90 of about 1,483,802 (353)

Mechanical property evaluation of an Al-2024 alloy subjected to HPT processing

, 2014
An aluminum-copper alloy (Al-2024) was successfully subjected to high-pressure torsion (HPT) up to five turns at room temperature under an applied pressure of 6.0 GPa.
Alhajeri, Saleh N., Das, Goutam, Das, Mousumi, Kori, S.A., Langdon, Terence G., Patil, Deepak C., Venkateswarlu, K.   +6 more
core   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Characterization of vertically aligned carbon nanotube forests grown on stainless steel surfaces [PDF]

, 2018
Vertically aligned carbon nanotube (CNT) forests are a particularly interesting class of nanomaterials, because they combine multifunctional properties, such as high energy absorption, compressive strength, recoverability and super-hydrophobicity with ...
Daraio, Chiara, Diamantopoulou, Marianna, Johanns, Paul, Parcianello, Giulio, Roumeli, Eleftheria, Serra-Garcia, Marc   +5 more
core   +3 more sources

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

Composite propellant technology research: Mechanical property characterization [PDF]

Proof for the existence of a single Poisson's ratio function in isotropic linear viscoelastic materials is presented. An in-depth discussion is given of three dimensional viscoelastic material properties and their relationships to linear isotropic and ...
Bower, Mark V.
core   +1 more source

Many Roads to Synchrony: Natural Time Scales and Their Algorithms [PDF]

, 2013
We consider two important time scales---the Markov and cryptic orders---that monitor how an observer synchronizes to a finitary stochastic process. We show how to compute these orders exactly and that they are most efficiently calculated from the epsilon-
A. S. Weigend, Christopher J. Ellison, D. Lind, J. E. Hopcroft, James P. Crutchfield, John R. Mahoney, K. Wiesner, L. E. Reichl, Robert B. Ash, Ryan G. James, T. H. Cormen, T. M. Cover   +11 more
core   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

Measurement of mechanical and thermophysical properties of dimensionally stable materials for space applications [PDF]

Mechanical, thermal, and physical property test data was generated for as-fabricated advanced composite materials at room temperature (RT), -150 and 250 F.
Misra, Mohan S., Rawal, Suraj P.
core   +1 more source

Nitrogen retention/enrichment of 316LN austenitic stainless steel welds [PDF]

, 2006
The development of nitrogen enriched austenitic stainless steels has been a source of recent interest due to the abundant availability of nitrogen and by the manner in which nitrogen contributes several beneficial material property effects over a wide ...
Galloway, Alexander, McPherson, Norman
core  

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source