Results 11 to 20 of about 779,679 (267)

The mechanical response of vinculin. [PDF]

open access: yesSci Adv
Vinculin is a mechanosensitive adaptor that links actin to cell-matrix and cell-cell adhesions. Known as a mechanoeffector, it is recruited to adhesion sites under force via mechanotransducers talin and α-catenin. Here, we examine vinculin’s mechanical properties to assess its role as a mechanotransducer.
Liu X   +8 more
europepmc   +3 more sources

The mechanical response of talin [PDF]

open access: yesNature Communications, 2016
AbstractTalin, a force-bearing cytoplasmic adapter essential for integrin-mediated cell adhesion, links the actin cytoskeleton to integrin-based cell–extracellular matrix adhesions at the plasma membrane. Its C-terminal rod domain, which contains 13 helical bundles, plays important roles in mechanosensing during cell adhesion and spreading.
Mingxi Yao   +8 more
openaire   +6 more sources

Imperfect Best-Response Mechanisms [PDF]

open access: yesTheory of Computing Systems, 2013
Best-response mechanisms (Nisan, Schapira, Valiant, Zohar, 2011) provide a unifying framework for studying various distributed protocols in which the participants are instructed to repeatedly best respond to each others' strategies. Two fundamental features of these mechanisms are convergence and incentive compatibility.
FERRAIOLI, DIODATO, P. Penna
openaire   +4 more sources

Mechanical Response of a Creased Sheet [PDF]

open access: yesPhysical Review Letters, 2014
5 pages, 6 figures, submitted to Physical Review ...
Lechenault, Frédéric   +2 more
openaire   +4 more sources

Molecular Mechanisms for the Mechanical Modulation of Airway Responsiveness [PDF]

open access: yesJournal of Engineering and Science in Medical Diagnostics and Therapy, 2019
The smooth muscle of the airways is exposed to continuously changing mechanical forces during normal breathing. The mechanical oscillations that occur during breathing have profound effects on airway tone and airway responsiveness both in experimental animals and humans in vivo and in isolated airway tissues in vitro.
Zhang, Wenwu, Gunst, Susan J.
openaire   +2 more sources

Mechanical response of coal rock mass with different proportions under true triaxial load

open access: yesMeikuang Anquan, 2021
In order to explore the mechanical response law of different coal rock proportion combinations under true triaxial load, the cube specimens with different combination methods were prepared.
DONG Hao
doaj   +1 more source

Research on mechanical response of buried steel pipelines under continuous collapse

open access: yesYou-qi chuyun, 2021
Formation collapse is one of the common geological hazards for the buried long-distance pipelines. In order to study the mechanical response law of the buried steel pipelines under continuous collapse, experiments and numerical simulations of buried ...
Peng LIU   +5 more
doaj   +1 more source

Mechanical Response of Pipeline Leakage to Existing Tunnel Structures: Insights from Numerical Modeling

open access: yesBuildings
Pipeline leakage can induce ground surface settlements and structural responses in existing tunnels. A thorough understanding of pipeline–tunnel interactions is crucial for optimizing urban underground design and establishing construction guidelines.
Ruichuan Zhao   +3 more
doaj   +1 more source

Study on Mechanical Characteristics of Shield Tunnels in Composite Strata Considering Segment Parameters

open access: yesChengshi guidao jiaotong yanjiu
[Objective] The influence of longitudinal stratum differences on tunnel structure under complex strata conditions is often ignored in shield tunnel design, resulting in the problem that although the structural design may meet construction requirements in
KANG Xiaoyue   +6 more
doaj   +1 more source

Mechanical response of X65 pipeline under rolling compaction of heavy trucks and the influencing factors

open access: yesYou-qi chuyun, 2022
With the acceleration of urbanization, more crossings of roads and pipelines appear, which poses some threat to the safety of pipeline operation. Taking X65 pipeline as the research object, the mechanical response of pipelines under three types of ...
Dong ZHANG   +6 more
doaj   +1 more source

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