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Effects of Mechanical Stress Stimulation on Function and Expression Mechanism of Osteoblasts
Frontiers in Bioengineering and Biotechnology, 2022 Osteoclasts and osteoblasts play a major role in bone tissue homeostasis. The homeostasis and integrity of bone tissue are maintained by ensuring a balance between osteoclastic and osteogenic activities.
Pan Liu +11 more
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Arthritis Research & Therapy, 2022 Background Mechanical stress plays a crucial role in the pathogenesis of intervertebral disc degeneration (IVDD). The mechanosensitive Piezo1 ion channel can sense the changes in mechanical stress and convert the mechanical signals into chemical signals.
Sheng Shi +5 more
semanticscholar +1 more source
Influence of Feed Motion on Surface Friction of AISI 1045 Steel Machined by a Fine-Grinding Process
Tribology in Industry, 2021 Fine-grinding is a final machining method used to reach the low friction and high-quality surface. The workspeed (vw) and crossfeed (vc) motions are perpendicular to each other and differ in value during the grinding process. Thus, the surface quality in
V.-H. Pham, T.-D. Nguyen
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Mechanical stress driven by rigidity sensing governs epithelial stability
bioRxiv, 2022 On soft substrates, epithelial tissues are under high tension and form holes that spontaneously heal. Thus, mechanical stress directly impacts the integrity of epithelia. Epithelia act as barriers against environmental stresses.
Surabhi Sonam +12 more
semanticscholar +1 more source
Influence of Humid Air Temperature on Friction Behavior in Pneumatic Cylinder
Tribology in Industry, 2021 In the air, water vapor always exists and impacts directly on the friction surface between the piston rod and the rod seal. Water vapor in the air forms moisture film on the surface of the piston rod. In some cases, it plays a role as a lubricant.
T.-D. Nguyen, V.-H. Pham
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Mechanical stress determines the configuration of TGFβ activation in articular cartilage
Nature Communications, 2021 Our incomplete understanding of osteoarthritis (OA) pathogenesis has significantly hindered the development of disease-modifying therapy. The functional relationship between subchondral bone (SB) and articular cartilage (AC) is unclear.
G. Zhen +14 more
semanticscholar +1 more source
Molecular Medicine, 2021 Apoptosis of chondrocyte is involved in osteoarthritis (OA) pathogenesis, and mechanical stress plays a key role in this process by activation of Piezo1. However, the negative regulation of signal conduction mediated by mechanical stress is still unclear.
Yi Sun +7 more
semanticscholar +1 more source
Analysis and Optimization of Defect Generation Due to Mechanical Stress in High-Density SRAM
IEEE Journal of the Electron Devices Society, 2021 Static random-access memory (SRAM) is an essential component for realizing large-scale integration (LSI). The future transition to a 48 V DC supply in datacenters and electric vehicles acting as mobile edge servers will increase the demand for a bipolar ...
Kazunari Ishimaru +2 more
doaj +1 more source
Maintaining proteostasis under mechanical stress
EMBO Reports, 2021 Cell survival, tissue integrity and organismal health depend on the ability to maintain functional protein networks even under conditions that threaten protein integrity.
J. Höhfeld +16 more
semanticscholar +1 more source
Targeting Mechano-Transcription Process as Therapeutic Intervention in Gastrointestinal Disorders
Frontiers in Pharmacology, 2021 Mechano-transcription is a process whereby mechanical stress alters gene expression. The gastrointestinal (GI) tract is composed of a series of hollow organs, often encountered by transient or persistent mechanical stress.
Ramasatyaveni Geesala +3 more
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