Results 241 to 250 of about 20,243,593 (306)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Piezo1-mediated Mechanotransduction in the musculoskeletal system: Signaling networks and therapeutic perspectives. [PDF]

open access: yesBone Rep
Zhao H   +11 more
europepmc   +1 more source

Effect of Various Root Canal Irrigation Techniques on Root Dentin Mechanical Properties: An In Vitro Study. [PDF]

open access: yesInt J Dent
AbuMostafa A   +6 more
europepmc   +1 more source

Machines, Mechanisms and Mechanical Systems

open access: yes
Dr. Suresh Ramchandra Nipanikar   +1 more
openaire   +1 more source

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