Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Multiphase PHA/PBAT/bacterial cellulose/starch biopolymer films: balancing high-temperature stability and controlled compostability. [PDF]
Hung DV, Diep NN, Hien HH, Hoang PH.
europepmc +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Reframing Hamstring Strain Injury Risk in Soccer: A Sprint Mechanism-Oriented 'Hardware-Software' Perspective. [PDF]
Mendiguchia J, Carmona G.
europepmc +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Piezo1-mediated Mechanotransduction in the musculoskeletal system: Signaling networks and therapeutic perspectives. [PDF]
Zhao H +11 more
europepmc +1 more source
Effect of Various Root Canal Irrigation Techniques on Root Dentin Mechanical Properties: An In Vitro Study. [PDF]
AbuMostafa A +6 more
europepmc +1 more source
Engineering principles in plant metabolism: integrating control, mechanics, and transport under dynamic environments. [PDF]
Nies T, Ebeling J, Matuszyńska A.
europepmc +1 more source
Machines, Mechanisms and Mechanical Systems
Dr. Suresh Ramchandra Nipanikar +1 more
openaire +1 more source
Development of a Low-Cost Portable System for Text-to-Speech Conversion: A Mechanical-Aided Optical Solution for Educational Inclusion. [PDF]
Rentería L +4 more
europepmc +1 more source

