Results 81 to 90 of about 1,690,858 (288)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Non-Contact Measurement of Small-Module Gears Using Optical Coherence Tomography
Applied Sciences, 2018 Due to the small size and harsh transmission conditions of small-module gears, it is very difficult to measure gear characteristics with a modulus smaller than 1 mm.
Manting Luo, Shuncong Zhong
doaj +1 more source
Design, fabrication, and structural testing of a lightweight shadow shield for deep-space application [PDF]
Two full-scale, lightweight, double-sheeted shadow shields were developed as the primary element of a deep-space thermal protection system for liquid-hydrogen propellant tankage.
Barber, J. R., Dewitt, R. L., Miao, D.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
International Journal of Electrical Power & Energy SystemsThe on-load tap changer (OLTC), widely used as a voltage regulation device in power systems, requires regular assessment and maintenance to ensure reliable operation and avoid adverse impacts on the power system.
Dongdong Song +4 more
doaj +1 more source
Applied Sciences, 2018 The transverse crack in a non-uniform shaft possesses different crack modes, and it can affect the propagation characteristics of the elastic waves in the shaft.
Yimin Wei, Xuan Shi, Qi Liu, Wenhua Chen
doaj +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Measurement of the Hissing-Type Noise and Vibration of the Automotive HVAC System
MATEC Web of Conferences, 2018 Noises such as hissing, humming, air-rush and compressor engagement are the common type of noises that can be induced from the automotive heating and ventilating air conditional (HVAC) system.
Paiman Muhammad Abdul Rahman +7 more
doaj +1 more source
Investigation of foamed metals for application on space capsules annual report, 29 jun. 1963 - 15 aug. 1964 [PDF]
Foamed metal development for space capsules - brazing, variable density beam, thermal testing, mechanical tests, and ...
Byrnes, E. +3 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source