Results 61 to 70 of about 585,172 (311)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Monitoring trabecular bone microdamage using a dynamic acousto-elastic testing method [PDF]

open access: yes, 2010
Dynamic acousto-elastic testing (DAET) is based on the coupling of a lowfrequency (LF) acoustic wave and high-frequency ultrasound (US) pulses (probing wave). It was developed to measure US viscoelastic and dissipative non-linearity in trabecular bone.
DEFONTAINE, Marielle   +11 more
core   +1 more source

Tunable Terahertz Plasmonic Sensor Based on Graphene/Insulator Stacks

open access: yesIEEE Photonics Journal, 2017
We propose a layer-by-layer graphene/insulator stacks based terahertz plasmonic sensor of refractive index of testing samples using a prism-coupling attenuated total reflection configuration.
Yi Huang   +3 more
doaj   +1 more source

Testing Mechanisms

open access: yesReview of Economic Studies
Abstract Economists are often interested in the mechanisms by which a treatment affects an outcome. We develop tests for the “sharp null of full mediation” that a treatment D affects an outcome Y only through a particular mechanism (or set of mechanisms) M.
Kwon, Soonwoo, Roth, Jonathan
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Characterization of Acoustic Emissions from Mechanical Seals for Fault Detection

open access: yes, 2014
The application of high-frequency Acoustic Emissions (AE) for mechanical seals diagnosis is gaining acceptance as a useful complimentary tool. This paper investigates the AE characteristics of mechanical seals under different rotational speed and fluid ...
Gu, Fengshou   +3 more
core  

High throughput mechanical property testing of materials libraries using a piezoelectric [PDF]

open access: yes, 2003
The present invention provides instruments and methods for screening combinatorial libraries that addresses many of the problems encountered when using conventional instruments.
Carlson, Eric D.   +9 more
core  

Spatiotemporal mapping of osteomyelitis pathogenesis guides the design of functionally graded bone regeneration scaffolds

open access: yesScientific Reports
Recurrent osteomyelitis remains a formidable challenge, with failure rates exceeding 25%. This study establishes a reproducible rabbit femoral model to systematically map the spatiotemporal pathogenesis of Staphylococcus aureus-induced osteomyelitis ...
Chenxin Wang   +11 more
doaj   +1 more source

Testing Nonassociative Quantum Mechanics

open access: yesPhysical Review Letters, 2015
The familiar concepts of state vectors and operators in quantum mechanics rely on associative products of observables. However, these notions do not apply to some exotic systems such as magnetic monopoles, which have long been known to lead to non-associative algebras. Their quantum physics has remained obscure.
Bojowald, Martin   +2 more
openaire   +4 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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