Results 51 to 60 of about 5,211,707 (295)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

A High Precision Capacitive Linear Displacement Sensor with Time-Grating that Provides Absolute Positioning Capability Based on a Vernier-Type Structure

Applied Sciences, 2018
Nanometer-scale measurement devices with high accuracy and absolute long-range positioning capability are increasingly demanded in the field of computer numerical control machining.
Xiaokang Liu, Hui Zhang, Kai Peng, Qifu Tang, Ziran Chen   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Contact reliability modeling and assessment of electrical connectors with multi-aperture slotted leaf spring contacts

Advances in Mechanical Engineering, 2023
Multi-aperture electrical connectors are widely used in the aerospace system to provide high-reliability and high-quality connections. The existing reliability assessment methods only focus on the single-aperture electrical connectors, and ignored the ...
Ping Qian, Zhen Ma, Wenhua Chen, Tong Zhang, Zhe Wang   +4 more
doaj   +1 more source

Testing Mechanisms

Review of Economic Studies
Abstract Economists are often interested in the mechanisms by which a treatment affects an outcome. We develop tests for the “sharp null of full mediation” that a treatment D affects an outcome Y only through a particular mechanism (or set of mechanisms) M.
Kwon, Soonwoo, Roth, Jonathan
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Repetitive Availability Demonstration Testing Procedure

, 2018
The proposed availability demonstration test (ADT) is an extension of the work of Usher and Taylor [Usher, J.S. and Taylor, G.D., "Availability Demonstration Testing," Qual. Reliab. Eng. Int., Vol. 22, No. 4, 2006, pp.
Usher, J. S., Aslam, M., Hardin, C. T., Jun, C. -H.   +3 more
core   +1 more source

A Review on Application of Pin-Fins in Enhancing Heat Transfer

Energies
The pin-fin is one of the main technologies in enhancing heat transfer. The accelerated flow and vortex structures are produced, which can disrupt the development of the flow boundary layer.
Tao Yang, Xiaoming Zhang, Zhenyuan Chang, Ran Xu, Jiaojiao Ma, Liang Xu, Lei Xi   +6 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source