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Preclinical modeling of mechanical thrombectomy

Journal of Biomechanics, 2022
Mechanical thrombectomy to treat large vessel occlusions (LVO) causing a stroke is one of the most effective treatments in medicine, with a number needed to treat to improve clinical outcomes as low as 2.6. As the name implies, it is a mechanical solution to a blocked artery and modeling these mechanics preclinically for device design, regulatory ...
Anagnostakou, Vania, Epshtein, Mark, Kuhn, Anna L., King, Robert M., Puri, Ajit S, Gounis, Matthew J   +5 more
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Mechanical Thrombectomy of M2-Occlusion

Journal of Stroke and Cerebrovascular Diseases, 2015
There is growing evidence for the efficacy of mechanical thrombectomy in acute stroke patients with large-vessel occlusions in the anterior circulation. Although distal occlusions of the middle cerebral artery (MCA) can cause severe clinical symptoms, endovascular therapy is not considered here as the first choice. The aim of our study was to prove the
Franziska Dorn, Henning Stetefeld, Christoph Kabbasch   +2 more
exaly   +3 more sources

Mechanical thrombectomy in acute ischemic stroke

Revue Neurologique, 2017
Recent randomized trials have demonstrated the efficacy of stent retriever thrombectomy, in association with intravenous thrombolysis, in acute ischemic stroke related to the occlusion of the distal internal carotid artery or the proximal middle cerebral artery within six hours of symptom onset.
Laurent Derex
exaly   +3 more sources

[Mechanical thrombectomy for acute ischemic stroke].

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2012
The therapy of acute ischemic stroke aims at fast recanalization of the occluded brain vessel. In contrast to intravenous thrombolysis (IVT), endovascular approaches yield higher recanalization rates especially in large vessel occlusions. Mechanical thrombectomy with the Merci Retriever received FDA approval in 2004 as an adjunct to IVT or in the case ...
Brekenfeld, C, Gralla, J, Zubler, Christoph, Schroth, G   +3 more
openaire   +3 more sources

A review of mechanical thrombectomy techniques for acute ischemic stroke

Interventional Neuroradiology, 2023
Mechanical thrombectomy is established as standard of care in the management of acute ischemic stroke due to large vessel occlusion and evidence-based guidelines for mechanical thrombectomy have been defined.
Alfredo Munoz
exaly   +1 more source

Patient Selection for Mechanical Thrombectomy

Clinical Neuroradiology, 2013
To evaluate the influence of tissue parameters as assessed by multimodal computed tomography and procedural parameters on clinical outcome after mechanical thrombectomy.A total of 301 consecutive patients with acute onset ischemic stroke were included in this study.
Nelles, Michael, Greschus, Susanne, Möhlenbruch, M., Simon, B., Wüllner, Ullrich, Urbach, Horst   +5 more
openaire   +3 more sources

Mechanical thrombectomy in patients with acute ischemic stroke: A cost-effectiveness and value of implementation analysis [PDF]

International Journal of Stroke, 2020
BACKGROUND Recent clinical trials have demonstrated the efficacy of mechanical thrombectomy in acute ischemic stroke. AIMS To determine the cost-effectiveness, value of future research, and value of implementation of mechanical thrombectomy ...
Robert Heggie, Olivia Wu, Phil White
exaly   +4 more sources

The “GP” Mechanical Thrombectomy Device

Journal of Stroke and Cerebrovascular Diseases, 2009
We present data concerning the extraction of clots using the newly invented "GP" mechanical thrombectomy device (MTD). Artificial and porcine clots of various lengths were used in plastic tube models of an artery. We investigate the pressures and times taken for clot extraction together with the volumes of fluid extracted.
Gillian, Pearce, Neil D, Perkinson, Julian, Wong, Matthew, Burley, Julian, Spence, Paul, Brookfield, David, Murcott   +6 more
openaire   +2 more sources

Mechanical thrombectomy for DVT

Techniques in Vascular and Interventional Radiology, 2004
Deep venous thrombosis is a common source of morbidity and mortality in the United States. Complications include pulmonary embolism and chronic post-thrombotic syndrome. Chronic post-thrombotic syndrome is characterized by extremity pain, edema, venous claudication, skin changes, and skin ulceration.
openaire   +2 more sources