Results 291 to 300 of about 2,602,339 (340)
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Journal of Thrombosis and Haemostasis, 2004
The delivery of encapsulated plasminogen activators has demonstrated enhanced thrombolysis in vivo in several models. The mechanism of such improvement has not previously been established.We explored in vitro the mechanism by which microencapsulation of streptokinase in polymeric microparticles accelerates clot digestion and reduces reperfusion times ...
J K, Leach, E, Patterson, E A, O'Rear
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The delivery of encapsulated plasminogen activators has demonstrated enhanced thrombolysis in vivo in several models. The mechanism of such improvement has not previously been established.We explored in vitro the mechanism by which microencapsulation of streptokinase in polymeric microparticles accelerates clot digestion and reduces reperfusion times ...
J K, Leach, E, Patterson, E A, O'Rear
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American Journal of Neuroradiology
This systematic review and meta-analysis evaluated the risk of intracerebral hemorrhage, and its subtypes associated with mechanical thrombectomy with or without IV thrombolysis for the treatment of acute ischemic stroke due to large-vessel occlusion ...
S. Jazayeri +6 more
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This systematic review and meta-analysis evaluated the risk of intracerebral hemorrhage, and its subtypes associated with mechanical thrombectomy with or without IV thrombolysis for the treatment of acute ischemic stroke due to large-vessel occlusion ...
S. Jazayeri +6 more
semanticscholar +1 more source
2001
The pharmacological use of plasminogen activators is associated with symptomatic improvement in patients with coronary artery thrombosis, peripheral arterial occlusions, and thrombosis of the venous system. Based on prospective angiographic studies and planned programs (1, 2, 3, 4, 5), thrombolysis is the only approved treatment of acute ischemic ...
Gregory J. Zoppo, Naohisa Hosomi
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The pharmacological use of plasminogen activators is associated with symptomatic improvement in patients with coronary artery thrombosis, peripheral arterial occlusions, and thrombosis of the venous system. Based on prospective angiographic studies and planned programs (1, 2, 3, 4, 5), thrombolysis is the only approved treatment of acute ischemic ...
Gregory J. Zoppo, Naohisa Hosomi
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[Percutaneous thrombectomy and mechanical thrombolysis].
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1998Treatment of acute embolic and thrombotic occlusions of arteries has to be initiated immediately to save the limb at risk. Surgery has been the treatment of choice for the last decades. Percutaneous mechanical methods for thrombectomy and thrombolysis have evolved and offer alternative treatment options, reducing the peri-operative risk.
J, Brossmann +2 more
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Mechanical Thrombolysis of Thrombosed Central Venous Port
CardioVascular and Interventional Radiology, 2014To evaluate the effectiveness of a mechanical thrombolysis for thrombosed central venous port (CVP).A total of 38 patients (22 women and 16 men, median age of 55 years) were referred to our interventional unit for thrombosed implanted CVPs. The period between CVP implantation and the initial suspicion of mechanical complication varied from 2 to 35 ...
Jung Suk, Oh +3 more
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Some Aspects of the Mechanism of Thrombolysis
Thrombosis and Haemostasis, 1961Summary1. Antibody to streptokinase and kinase, activator and plasmin inhibitors in the circulating blood of man, inhibit parenterally injected streptokinase and streptokinase-plasmin, in vivo. In vitro assays of these inhibitors determine the priming dose of streptokinase and streptokinase-plasmin to neutralize the inhibitors and effect thrombolysis.2.
A J, JOHNSON, W R, McCARTY
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Intravenous thrombolysis prior to mechanical thrombectomy in large vessel occlusions
Annals of Neurology, 2019The substantial clinical improvement in acute ischemic stroke (AIS) patients treated with mechanical thrombectomy (MT), combined with the poor response of proximal intracranial occlusions to intravenous thrombolysis (IVT), led to questions regarding the ...
A. Katsanos +14 more
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Thrombolysis and mechanical thrombectomy for arterial disease
Surgical Clinics of North America, 2004Thrombolytic therapy has been around for close to 30 years now,but its exact role in the treatment of acute and chronic arterial occlusive disease continues to be debated. Studies have produced varying and contradictory results. We are still not sure if thrombolysis has any true advantages over surgical thromboembolectomy,or which lytic agent is the ...
Zachary C, Schmittling, Kim J, Hodgson
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Successful thrombolysis on a mechanical tricuspid prosthesis
European Heart Journal, 1989Recombinant tissue-type plasminogen activator (rt-PA) is presently used for the treatment of different clinical entities, mostly myocardial infarction. Its use for treatment of thrombotic dysfunction of prosthetic cardiac valves is more recent and has been only rarely reported.
M A, Prieto Palomino +6 more
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Molecular mechanisms of thrombolysis: Implications for therapy
Biochemical Pharmacology, 1990The review deals with the molecular mechanism of action and with the thrombolytic properties of streptokinase, recombinant tissue-type plasminogen activator and anisoylated plasminogen streptokinase activator complex (APSAC)
D, Collen, H R, Lijnen
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