Results 241 to 250 of about 80,331 (298)

Departing from standard practices: Strategic application of value engineering in the anatomy laboratory to enhance formaldehyde extraction using high‐impact, low‐cost, and low‐maintenance solutions

Anatomical Sciences Education, Volume 18, Issue 3, Page 241-253, March 2025.
Abstract This study describes the process of developing a high‐impact, low‐cost, and low‐maintenance air ventilation system for anatomy facilities. It employed the strategic application of Value Engineering (VE), assuring that the air ventilation system meets contemporary threshold limit values (TLVs) for formaldehyde in the working zone of dissection ...
Jürgen Russ, Niels Hammer
wiley   +1 more source

Operationalizing BioSSbD: A safe‐and‐sustainable‐by‐design framework for biorefineries

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Biorefineries are central to the transition toward a circular bioeconomy; however, their increasing scale and technological heterogeneity, and the integration of biological, chemical, and thermochemical processes introduce complex challenges related to safety, sustainability, and operational reliability. Existing Safe‐and‐Sustainable‐by‐Design
Fernando Ramonet
wiley   +1 more source

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

British Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić, Elvira Meni Maria Gkrinia, Patrick Eustaquio, Andrea Katrin Faour, Dinko Vitezić   +4 more
wiley   +1 more source

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

British Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić, Ivana Stević, Elvira Meni Maria Gkrinia, Dinko Vitezić, Slobodan Janković   +4 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

10D: Feasibility Study of a Novel Low-cost Brazilian Emergency Mechanical Ventilator

, 2020
Flato UAP, Santos PCd, Manhoso F, Serva FM, Dias J, Bueno CE, Garbelini G, Biteli P, Scorsato P, Friolani M, Repetti C, Franco RP, Piai M, Silva Ld, Porto C, Cunha Id, Pereira ER, Bueno B, Buchaim D, Buchaim R, Peres S, Peres M, Peres A, Narciso A, Ramires D, Teixeira D, Fujikawa F, Bezerra F, Habache J, Bonzanini J, Laureano J, Pansani L, Cavachioli M, Pansani M, Martins M, Souza MRd, Filho OO, Santos Wd, Fregatto LF, Novaretti JP, Reis CH, Cremonez CM, Serva MM.   +42 more
europepmc   +1 more source

Emergency Mechanical Ventilator Design: Low-Cost and Accessible Components [PDF]

Electronics (Switzerland), 2022
This paper presents the fundamentals; criteria; and mechanical, electrical, and electronic aspects required to properly operate and control emerging mechanical ventilators.
Jorge Mauricio Fuentes, Henry Carvajal, Patricia Acosta-Vargas   +2 more
exaly   +5 more sources

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Ventilation Mechanics

Seminars in Respiratory and Critical Care Medicine, 2023
AbstractA fundamental task of the respiratory system is to operate as a mechanical gas pump ensuring that fresh air gets in close contact with the blood circulating through the lung capillaries to achieve O2 and CO2 exchange. To ventilate the lungs, the respiratory muscles provide the pressure required to overcome the viscoelastic mechanical load of ...
Ramon, Farré, Daniel, Navajas
openaire   +2 more sources

Mechanical Ventilation

DICP, 1990
Among the many advances made in intensive care therapeutics in recent years, few have rivaled the impact of mechanical ventilators. Their expanded use affects all who practice in the critical care setting. This article reviews the physiologic basis for mechanical ventilation, how ventilators are classified, the various modes, and specific indications ...
R A, Barbarash, L A, Smith, J E, Godwin, S A, Sahn   +3 more
openaire   +2 more sources