Results 31 to 40 of about 121,296 (347)

Mechanical power in pediatric acute respiratory distress syndrome: a PARDIE study

open access: yesCritical Care, 2022
Background Mechanical power is a composite variable for energy transmitted to the respiratory system over time that may better capture risk for ventilator-induced lung injury than individual ventilator management components.
Anoopindar K. Bhalla   +19 more
doaj   +1 more source

Effect of external PEEP in patients under controlled mechanical ventilation with an auto-PEEP of 5 cmH2O or higher. [PDF]

open access: yes, 2016
In some patients with auto-positive end-expiratory pressure (auto-PEEP), application of PEEP lower than auto-PEEP maintains a constant total PEEP, therefore reducing the inspiratory threshold load without detrimental cardiovascular or respiratory effects.
Amodeo, Guido   +16 more
core   +1 more source

TRPV4-A Missing Link Between Mechanosensation and Immunity [PDF]

open access: yes, 2020
Transient receptor potential vanilloid-type 4 (TRPV4) cation channel is widely expressed in all tissues as well as in immune cells and its function as mechanosensitive Ca2+ channel seems to be conserved throughout all mammalian species. Of late, emerging
Kuebler, Wolfgang M., Michalick, Laura
core   +1 more source

Risk factors for ventilator-associated pneumonia in trauma patients with torso injury: a retrospective single-center study

open access: yesJournal of International Medical Research, 2021
Objective We aimed to identify the risk factors for ventilator-associated pneumonia in patients admitted to critical care after a torso injury. Methods We retrospectively evaluated 178 patients with torso injury aged >15 years who were intubated in the ...
Jin Young Lee   +7 more
doaj   +1 more source

The implausibility of ‘usual care’ in an open system: sedation and weaning practices in Paediatric Intensive Care Units (PICUs) in the United Kingdom (UK) [PDF]

open access: yes, 2015
Background: The power of the randomised controlled trial depends upon its capacity to operate in a closed system whereby the intervention is the only causal force acting upon the experimental group and absent in the control group, permitting a valid ...
B Ambuel   +34 more
core   +1 more source

Automated mechanical ventilation using Adaptive Support Ventilation versus conventional ventilation including ventilator length of stay, mortality, and professional social aspects of adoption of new technology

open access: yesJournal of Mechanical Ventilation, 2021
Background Automation of mechanical ventilation allows for reduction of variation in patient management and has the potential to provide increased patient safety by strict adherence to computer driven ventilator protocols.
Ronald R. Sanderson   +2 more
doaj   +1 more source

PVP1-The People's Ventilator Project: A fully open, low-cost, pressure-controlled ventilator research platform compatible with adult and pediatric uses.

open access: yesPLoS ONE, 2022
Mechanical ventilators are safety-critical devices that help patients breathe, commonly found in hospital intensive care units (ICUs)-yet, the high costs and proprietary nature of commercial ventilators inhibit their use as an educational and research ...
Julienne LaChance   +10 more
doaj   +2 more sources

Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration. [PDF]

open access: yesPLoS ONE, 2015
BACKGROUND:Ventilator-induced lung injury is a form of acute lung injury that develops in critically ill patients on mechanical ventilation and has a high degree of mortality. Nicotinamide phosphoribosyltransferase is an enzyme that is highly upregulated
Heather D Jones   +10 more
doaj   +1 more source

Prevention of ventilator-associated pneumonia in intensive care units: an international online survey [PDF]

open access: yes, 2013
Background: On average 7% of patients admitted to intensive-care units (ICUs) suffer from a potentially preventable ventilator-associated pneumonia (VAP). Our objective was to survey attitudes and practices of ICUs doctors in the field of VAP prevention.
Agodi, Antonella   +8 more
core   +4 more sources

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