Results 141 to 150 of about 2,415,464 (295)

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Mechanical Ventilation [PDF]

Annals of Emergency Medicine, 2018
openaire   +2 more sources

A Fast Response, High Flow Rate, Low Power Consumption Pneumatic Proportional Valve for Medical Ventilators Driven by a Piezoelectric Bimorph

Actuators
In recent years, pneumatic proportional valves have become increasingly prevalent in ventilators, particularly proportional solenoid valves. However, these traditional valves face challenges, including a slow response, being prone to overheating from ...
Shuai Ren, Junling Chen, Tao Wang, Bingbing Ma   +3 more
doaj   +1 more source

Adaptive and Highly Efficient Thermoregulation Based on Multi‐Dimensional Janus Film

Advanced Science, EarlyView.
A switchable TiO2/MXene/PDMS Janus membrane enables dual‐mode radiative cooling and solar heating, achieving sub‐ambient cooling of 17.89°C and above‐ambient heating of 13.82°C. Adaptive temperature regulation was demonstrated with a low power integrated autonomous smart curtain system, providing a sustainable and energy‐efficient alternative for ...
Yuqing Shi, Yuting Fu, Xiong Yu, Yuao Guo, Yanjun Liu, Dan Luo, Yuanjing Lin   +6 more
wiley   +1 more source

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

Advanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen, Xiongfeng He, Zihao Li, Zidong Chen, Jiajin Sun, Xinyu Jiang, Yunhui Zhang, Lizhang Wu, Ran Wang, Jingnan Lu, Bo Wang, Kezhou Cai, Baocai Xu   +12 more
wiley   +1 more source

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

Advanced Science, EarlyView.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae, Jisun Lee, Jae‐Hun Ahn, Hosam Choi, Huijeong Choi, Jungmin Kim, Minho Kang, Ho Rim Oh, So Hyun Park, Eun Young Oh, Sanghyuk Jeon, Yeeun Lee, Yu‐Sun Lee, Na‐Young Lee, Hee‐Jin Bae, Jina Kwak, Jooil Kim, Nakyung Lee, Beomsun Kang, Ji‐Hye Kim, Eunsaem Song, Daesub Song, Hyunho Yoon, Sang‐Myeong Lee, Hyewon Youn, Kiyoun Lee, Byeong‐Cheol Kang, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Evaluation of the knowledge and practice among intensive care physicians (Intensivists) in Egypt

Egyptian Journal of Chest Disease and Tuberculosis
Context ICU doctors offer 24-hour bedside care for critically ill patients. They may put established preventive methods into clinical practice and play a key role in preventing, controlling, and treating hospital-acquired infections in intubated patients.
Miral Al-Sherif, Nezar Rifaat, Elham Abd Elhady Abd Elghany, Mohammed T. Abdelfatah, Wagdy Amin, Lucy A. Suliman, Manar S. Mohamed   +6 more
doaj   +1 more source

The comparison of ventilation parameters of anesthesia ventilators and ICU ventilators [PDF]

, 2018
Cílem práce bylo porovnání přesnosti dodávané ventilační podpory, hladiny PEEP a rychlosti odezvy ventilátoru na dechové úsilí modelu plic za použití synchronizovaných ventilačních režimů mezi anesteziologickými ventilátory a ventilátory používanými na ...
Kloudová Aneta
core  

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

Performance Characteristics of Five New Anesthesia Ventilators and Four Intensive Care Ventilators in Pressure-support Mode

Background During the past few years, many manufacturers have introduced new modes of ventilation in anesthesia ventilators, especially partial-pressure modalities. The current bench test study was designed to compare
Eledjam, Jean-Jacques, Sebbane, Mustapha, Capdevila, Xavier, Battisti, Anne, Pouzeratte, Yvan, Tassaux, Didier, Jaber, Samir, Jolliet, Philippe   +7 more
core   +1 more source