Results 21 to 30 of about 96,271 (199)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Structural Optimization of Tri-Cone Cyclone Based on the Response Surface Method

Shiyou jixie
There are scarce reports on the separation performance of discontinuous multi-cone cyclones. This paper presents a combined tricone cyclone structure. First， a numerical simulation was conducted for single factor analysis on the main structure， so as to ...
Qian Weifeng, Zhou Sizhu, Zhuang Hao, Huang Tiancheng, Yao Zhoukun   +4 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Effect of a Nonlinear Energy Sink on the Nonlinear Panel Flutter Suppression Under Variable Temperature Rise and Airflow Yawed Angle

International Journal of Aerospace Engineering
This study investigates the nonlinear aeroelastic response behaviors and robustness of a square isotropic panel with a nonlinear energy sink (NES) considering temperature rise and airflow yawed angle.
Zhou Jian, Guo Yilin, Gao Zehao, Xu Minglong   +3 more
doaj   +1 more source

A Component-Based Parametric Reduced-Order Modeling Method Combined with Substructural Matrix Interpolation and Automatic Sampling

Shock and Vibration, 2019
An efficient parametric reduced-order modeling method combined with substructural matrix interpolation and automatic sampling procedure is proposed. This approach is based on the fixed-interface Craig-Bampton component mode synthesis method (CMS).
Ying Liu, Hongguang Li, Yun Li, Huanyu Du   +3 more
doaj   +1 more source

Domain Adaptive Motor Fault Diagnosis Using Deep Transfer Learning

IEEE Access, 2019
Motor fault diagnosis based on deep learning frameworks has gained much attention from academic research and industry to guarantee motor reliability. Those methods are commonly under two default assumptions: 1) massive labeled training samples and 2) the
Dengyu Xiao, Yixiang Huang, Lujie Zhao, Chengjin Qin, Haotian Shi, Chengliang Liu   +5 more
doaj   +1 more source

Hysteresis Modeling and Compensation of Piezoelectric Actuators Using Gaussian Process with High-Dimensional Input

Actuators, 2022
Rate-dependent hysteresis seriously deteriorates the positioning accuracy of the piezoelectric actuators, especially when tracking high-frequency signals.
Yixuan Meng, Xiangyuan Wang, Linlin Li, Weiwei Huang, Limin Zhu   +4 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source