Results 101 to 110 of about 516,257 (296)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
, 2011 a) Topics and goals. The aim of group D-III-3 »Mechanics« is to investigate the Aristotelian Mechanica as a mathematical discipline in the context of Aristotle’s natural philosophy. Especially relevant for the group’s research is the question of how geometric discourse, spatial models, and diagrammatic representation are employed in these different but
Harlfinger, Dieter +2 more
openaire +2 more sources
What Factors Do Players Perceive as Methods of Retention in Battle Royale Games?
Press Start, 2022 Battle Royale (BR) games are well known for their ability to not only attract but also retain a large number of players. In this paper, we attempt to identify the common themes which BR players identify as methods of retention through a qualitative ...
Michael John Saiger +1 more
doaj
The Mechanics of the "L.E." Cell Phenomenon, Studied with a Simplified Test [PDF]
, 1955 I. Snapper, Daniel J. Nathan
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Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
Mechanics of Schrodinger mechanics
, 2004 Small perturbations of ideal turbulence obey the Schrodinger equation. Microscopically, the perturbation of turbulence corresponds to formation of small amplitude helices on straight vortex filaments. A helix behaves in the vorticity field of the fluid as a spin particle in the Stern-Gerlach experiment.
openaire +2 more sources
Biophysics and Physicobiology, 2019 Organs and tissues in multi-cellular organisms exhibit various morphologies. Tubular organs have multi-scale morphological features which are closely related to their functions. Here we discuss morphogenesis and the mechanical functions of the vertebrate
Hiroshi Koyama +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source