Results 91 to 100 of about 1,023,504 (293)

The wheel has already been invented: Facilitating students' use of existing mechanics resources [PDF]

open access: yes, 2010
Weve been teaching engineering mechanics to first year engineering students for a long time, yet at many engineering faculties around the world there are still significant failure rates⋯ Educators have tried many different approaches to address ...
Gardner, A, Goldfinch, T
core  

Self-Organization at the Nanoscale Scale in Far-From-Equilibrium Surface Reactions and Copolymerizations

open access: yes, 2012
An overview is given of theoretical progress on self-organization at the nanoscale in reactive systems of heterogeneous catalysis observed by field emission microscopy techniques and at the molecular scale in copolymerization processes.
Gaspard, Pierre
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

A multimedia visualization tool for solving mechanics dynamics problem [PDF]

open access: yes, 2005
The objective of this research is to complement and enhanced traditional tutorial teaching and learning by incorporating multimedia technology. In this case study, the development of a PC base virtual experiment for mechanics dynamics problem involving ...
Manjit Sidhu, S.   +2 more
core  

Mechanics of a Plant in Fluid Flow

open access: yes, 2019
Plants live in constantly moving fluid, whether air or water. In response to the loads associated with fluid motion, plants bend and twist, often with great amplitude. These large deformations are not found in traditional engineering application and thus
Gosselin, Frederick P.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Emerging Trends in Structural Mechanics Education: A Bibliometric Approach from the Perspective of Colombian Professors

open access: yesBuildings
Recent developments in higher education have transformed teaching–learning processes across disciplines, including structural mechanics in civil engineering programs.
Jesús D. Villalba-Morales   +7 more
doaj   +1 more source

Systems of coding and their implementation [PDF]

open access: yes, 1971
Engineering planning document surveys mechanics, utility, and potential improvements of codes which control noise-generated errors introduced into radio transmission of binary information.
Anderson, T. O.
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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