Results 41 to 50 of about 1,023,504 (293)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Biomechanics [PDF]

open access: yes, 2012
Biomechanics is a vast discipline within the field of Biomedical Engineering. It explores the underlying mechanics of how biological and physiological systems move.
Harris, Gerald F, Slavens, Brooke A.
core   +1 more source

Necessary Optimality Conditions for a Dead Oil Isotherm Optimal Control Problem

open access: yes, 2006
We study a system of nonlinear partial differential equations resulting from the traditional modelling of oil engineering within the framework of the mechanics of a continuous medium.
A. Bensoussan   +13 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Marine Structures

open access: yesJournal of Marine Science and Engineering, 2019
Structural mechanics is an important field of engineering [...]
Erkan Oterkus
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Professor Algirdas Čižas as famous scientist and educator/Profesorius Algirdas Čižas - žymus mokslininkas ir pedagogas

open access: yesJournal of Civil Engineering and Management, 1999
Algirdas Eduardas ČIžas is Professor of the Department of Strength of Materials, Director of the Lithuanian Centre for Quality Assessment in Higher Education. Prof A. Čižas was born on September 16, 1929 in a picturesque Lithuanian locality, Anykščiai.
Juozas Atkočiūnas
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Implementation of a visualization teaching approach for mechanical analysis in civil engineering structures

open access: yesEngineering Reports
The visualization method for mechanics knowledge in civil engineering courses is very important, which can help students learn abstract mechanics. Combined with the structural analysis software, this paper develops a visualization teaching approach for ...
Panxu Sun   +3 more
doaj   +1 more source

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