Results 81 to 90 of about 1,023,504 (293)
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Research in nonlinear structural and solid mechanics [PDF]
Recent and projected advances in applied mechanics, numerical analysis, computer hardware and engineering software, and their impact on modeling and solution techniques in nonlinear structural and solid mechanics are discussed.
Mccomb, H. G., Jr., Noor, A. K.
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Progressive failure methodologies for predicting residual strength and life of laminated composites [PDF]
Two progressive failure methodologies currently under development by the Mechanics of Materials Branch at NASA Langley Research Center are discussed. The damage tolerance/fail safety methodology developed by O'Brien is an engineering approach to ensuring
Allen, David H. +2 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Research Progress and Engineering Applications of Viscous Fluid Mechanics
Applied SciencesThis paper systematically reviews the development of viscous fluid mechanics and expounds the current research status of viscous fluid mechanics from the aspects of permeability experiments and research on viscous fluids, particle distribution and ...
Jianjun Peng +6 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Exploration and practice in digital rock mechanics engineering
Meitan kexue jishuTraditional mining engineering has long been trapped in the dilemma of “coexistence of mining operations and inherent risks”. The duality of its high-risk nature and resource contribution has become increasingly prominent under deep mining conditions. As
Hegang QI +12 more
doaj +1 more source
Role of unsaturated soil mechanics in geotechnical engineering
International Journal of Geo-Engineering, 2019 The understanding of unsaturated soil mechanics principles is of interest to a wide spectrum of geotechnical problems associated with soils above water table and compacted soils.
Harianto Rahardjo +2 more
doaj +1 more source