Results 21 to 30 of about 219,378 (217)

Digital rock mechanics solutions for underground engineering problems such as coal mining

open access: yesMeitan kexue jishu
The observability of underground engineering, such as coal mining, is extremely limited, which makes it difficult to obtain reliable pre-analysis basis for many complex engineering problems. Especially in face of new engineering environment brought about
Haitao LI   +12 more
doaj   +1 more source

Role of unsaturated soil mechanics in geotechnical engineering

open access: yesInternational Journal of Geo-Engineering, 2019
The understanding of unsaturated soil mechanics principles is of interest to a wide spectrum of geotechnical problems associated with soils above water table and compacted soils.
Harianto Rahardjo   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

A CASE STUDY IN PROJECT BASED LEARNING USING FLOW VISUALISATION [PDF]

open access: yesJournal of Engineering Science and Technology, 2007
Engineering Design modules, usually introduced in the first and second year’s undergraduate Mechanical Engineering courses, present a unique platform to practice the Project Based Learning (PBL).
MUSHTAK AL-ATABI, S.B. CHIN
doaj  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Professor Algirdas Čižas as famous scientist and educator/Profesorius Algirdas Čižas - žymus mokslininkas ir pedagogas

open access: yesJournal of Civil Engineering and Management, 1999
Algirdas Eduardas ČIžas is Professor of the Department of Strength of Materials, Director of the Lithuanian Centre for Quality Assessment in Higher Education. Prof A. Čižas was born on September 16, 1929 in a picturesque Lithuanian locality, Anykščiai.
Juozas Atkočiūnas
doaj   +1 more source

The Role of Applied Mechanics in Bridging the Gaps in Prior Learning for Aspirants of Engineering Education

open access: yesEducation Sciences, 2021
Building a technology-driven world appears to be the main motivational force behind students choosing to undertake engineering studies. The first year of engineering education plays a significant role in demonstrating sufficient mathematical and ...
Sarat Singamneni
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Mathematics in Finite Element Modeling of Computational Friction Contact Mechanics 2021–2022

open access: yesMathematics, 2023
In engineering practice, structures with identical components or parts are useful from several points of view: less information is needed to describe the system; designs can be conceptualized quicker and easier; components are made faster than during ...
Nicolae Pop, Marin Marin, Sorin Vlase
doaj   +1 more source

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