Results 71 to 80 of about 173,631,140 (304)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Mechanics of materials and structures /
, 1994 A wide range of topics in the area of mechanics of materials and structures are covered in this volume, ranging from analysis to design. There is no special emphasis on a specific area of research.
Bieniek Symposium on Mechanics of Materials and Structures(1993 :University of Virginia) +4 more
core
introduction to the special jmp issue: statistical mechanics on random structures
, 2008 Introduzione al numero speciale di JMP "statistical mechanics on random ...
cristian Giardina, CONTUCCI, PIERLUIGI
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
A modelling technique for calculating stress intensity factors for structures reinforced by bonded straps. Part I: Mechanisms and formulation [PDF]
, 2010 This paper describes a 2D FE modelling technique for predicting fatigue crack growth life of integral structures reinforced by bonded straps. This kind of design offers a solution to the intrinsic lack of damage tolerance of integral structures.
Boscolo, Marco +3 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
MetalsIn the context of an increasing interest in the use of high-performance steels in the construction industry due to their superior mechanical properties, understanding the behaviour and assessing the performance of dissimilar welded connections becomes ...
Anna Ene, Aurel Stratan, Ioan Both
doaj +1 more source
Theoretical justification of the kinematic parameter of the rotary working body [PDF]
E3S Web of ConferencesThis article presents a method for calculating the working body of a cultivator in the form of a rotary knife drum. Since the knives on the drum are arranged radially, the ends of the knives under the translational movement of the rotary drum describe ...
Yuldashev Abdurakhim +4 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
RETRACTED: Experiments on pressing elastic-viscous products [PDF]
BIO Web of ConferencesSee the retraction notice BIO Web of Conferences 138, 00001 (2024), https://doi.org/10.1051/bioconf ...
Bahadirov Gayrat +2 more
doaj +1 more source