Results 111 to 120 of about 11,573,862 (305)

A Typed Language for Truthful One-Dimensional Mechanism Design [PDF]

, 2008
We first introduce a very simple typed language for expressing allocation algorithms that allows automatic verification that an algorithm is monotonic and therefore truthful.
Lapets, Andrei, Levin, Alex, Parkes, David   +2 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Efficacy and safety of low-dose interleukin 2 for Behçet’s syndrome: a randomized, placebo-controlled, double-blind, phase 2 clinical trial

Nature Communications
Behçet’s syndrome (BS), a chronic vasculitis, leads to recurrent oral ulcers, severely impacting quality of life. Here we report the results of a randomized, double-blind, placebo-controlled trial (NCT04065672) to evaluate the efficacy and safety of low ...
Tian Liu, Wenyan Zhou, Yan Zhu, Weiyi Xia, Jiali Chen, Xian Xiao, Bo Huang, Ruiling Feng, Hua Ye, Shi Chen, Xiaoying Zhang, Miao Shao, Chun Li, Yuan Jia, Miao Miao, Yuebo Jin, Xue Li, Xia Zhang, Yunshan Zhou, Ru Li, Xuewu Zhang, Yin Su, Huixin Liu, Jing Li, Fanlei Hu, Jianping Guo, Xiaolin Sun, Jing He, Zhanguo Li   +28 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

A European mechanism for sovereign debt crisis resolution: a proposal [PDF]

This Bruegel Blueprint argues that Europe should take the lead in defining a solution to the problem of excessive public debts and create a European Crisis Resolution Mechanism (ECRM).The authors, Francois Gianviti, Anne O.
André Sapir, Anne O. Krueger, Francois Gianviti, Jean Pisani-Ferry, Jürgen von Hagen   +4 more
core   +1 more source

Hydraulic drive mechanism Patent [PDF]

, 1967
Hydraulic drive mechanism for leveling isolation ...
Tsutsumi, K.
core   +1 more source

Mechanism of Gravity Impulse

, 2005
It is well-known that energy-momentum is the source of gravitational field. For a long time, it is generally believed that only stars with huge masses can generate strong gravitational field.
, A. Westphal, Albert Einstein, E. Podkletnov, E. Podkletnov, E. Podkletnov, Isaac Newton, Ning WU, Ning WU, Ning WU, Ning WU, Ning WU, Ning WU, Ning WU, Ning WU, Ning Wu, Ning WU, Ning WU, Ning WU, Ning WU, Ning WU, Ning WU, Ning WU, Ning WU, Ning WU, Ning Wu, Ning Wu, Ning WU, Wu Ning   +28 more
core   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Tethered satellite control mechanism [PDF]

, 1983
The tethered satellite control mechanisms consist of four major subsystems. The reel drive mechanism stores the tether. It is motor driven and includes a level wind to uniformly feed the tether to the reel.
Kyrias, G. M.
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source