Results 131 to 140 of about 11,658,941 (310)

A Typed Language for Truthful One-Dimensional Mechanism Design [PDF]

open access: yes, 2008
We first introduce a very simple typed language for expressing allocation algorithms that allows automatic verification that an algorithm is monotonic and therefore truthful.
Lapets, Andrei   +2 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Theoretical understanding and technical practice of shale oil development in continental faulted basins in eastern China: A case study of Jiyang shale oil

open access: yesYouqi dizhi yu caishoulu
The shale oil in the continental faulted basins in eastern China,represented by Jiyang shale oil,has made a breakthrough in production capacity. However,Jiyang shale oil faces great challenges in achieving high and stable production due to the large ...
YANG Yong   +9 more
doaj   +1 more source

Bidirectional drive and brake mechanism [PDF]

open access: yes, 1991
A space transport vehicle is disclosed as including a body which is arranged to be movably mounted on an elongated guide member disposed in outer space and driven therealong.
Swan, Scott A.
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Cherenkov-drift emission mechanism [PDF]

open access: yes, 1998
Emission of a charged particle propagating in a medium with a curved magnetic field is reconsidered stressing the analogy between this emission mechanism and collective Cherenkov-type plasma emission.
Blandford, Roger   +2 more
core   +1 more source

Mechanisms

open access: yesDeutsches Ärzteblatt international, 2021
openaire   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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