Results 41 to 50 of about 4,500,819 (268)
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar +7 more
wiley +1 more source
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot +6 more
wiley +1 more source
To address the strongly coupled and highly nonlinear optimization problems arising from the increasing system complexity, optimization objectives, and variable dimensions in practical engineering applications, this paper proposes a multi-strategy ...
Fan Yang +5 more
doaj +1 more source
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source
To address the challenge of simulating force–thermal environmental loads on morphing wings during flight, this study proposes and validates a force–thermal simulation method based on servo loading. First, the aerodynamic loads on a multi-stage telescopic
Hong Xiao +6 more
doaj +1 more source
Mechanisms of Teratogenesis [PDF]
Man’s early pictorial and written records make it clear that he was aware of and curious about the structural defects that from birth afflicted some of his fellow men. His attitudes about these congenital variants have ranged widely in different cultures: from romanticizing them in mythology, to using them as portent of coming events, to accepting them
openaire +2 more sources
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita +5 more
wiley +1 more source
Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte +5 more
wiley +1 more source
Transient mechanisms are increasingly applied in fields such as high-speed aircraft, super high-speed trains, and underwater robots. However, in high-speed motion, large inertial forces are inevitably generated, which can easily lead to elastic ...
Yue Bai +7 more
doaj +1 more source

