Results 61 to 70 of about 11,658,941 (310)

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Latching mechanism Patent [PDF]

open access: yes, 1971
Latch for fastening spacecraft docking ...
Cobin, J. C., Rhodes, L. L.
core   +1 more source

In defense of mechanism [PDF]

open access: yes, 2006
In Life Itself and in Essays on Life Itself, Robert Rosen (1991, 2000) argued that machines were, in principle, incapable of modeling the defining feature of living systems, which he claimed to be the existence of closed causal loops.
Wells, Andrew J.
core   +1 more source

Mechanisms and mechanics of auditory masking

open access: yesThe Journal of Physiology, 2013
It is rare to hear just one sound at a time. More often than not, our experience of listening to someone speak, or hearing a piece of music, is made more challenging, and possibly more annoying, by the presence of interfering sound, be it traffic noise, air-conditioning rumble, or other people talking at the same time. In extreme situations, such as in
openaire   +3 more sources

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman   +7 more
wiley   +1 more source

Dynamically assisted Schwinger mechanism

open access: yes, 2008
We study electron-positron pair creation {from} the Dirac vacuum induced by a strong and slowly varying electric field (Schwinger effect) which is superimposed by a weak and rapidly changing electromagnetic field (dynamical pair creation).
A. I. Nikishov   +14 more
core   +1 more source

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason   +14 more
wiley   +1 more source

The mechanical characteristics analysis of the telescopic wing with adaptive driving mechanism

open access: yesAdvances in Mechanical Engineering
The deflection of the high aspect ratio telescopic wing is inevitable under aerodynamic force. It is of great significance to ensure that the internal mechanism can exercise smoothly in the deformation state.
Chunfeng Li   +5 more
doaj   +1 more source

Size optimization method of the Watt-II six-bar mechanism based on particle swarm optimization [PDF]

open access: yesMechanical Sciences
Aiming at the difficult problem of comprehensive scale design of the six-bar mechanism in engineering practice, kinematic and dynamic analysis and modeling of the Watt-II six-bar mechanism were carried out and combined with the particle swarm ...
H. Ye   +13 more
doaj   +1 more source

THE MECHANICS AND MECHANISMS OF TOURISM BROKERING

open access: yesEthnologia Europaea, 2018
Although most forms of tourism are, and have always been, highly mediated activities, surprisingly little scholarly attention has been given to the crucial role of human brokers in tourism.
openaire   +2 more sources

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