Results 61 to 70 of about 11,555,627 (307)
Applied SciencesTransient mechanisms are increasingly applied in fields such as high-speed aircraft, super high-speed trains, and underwater robots. However, in high-speed motion, large inertial forces are inevitably generated, which can easily lead to elastic ...
Yue Bai +7 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Connection space reduction mechanism [PDF]
, 1992 A connector assembly comprised of two halves, each respectively including a shell type connector subassembly, one being an active half and the other being a passive half is described.
Milam, Malcolm Bruce
core +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Size optimization method of the Watt-II six-bar mechanism based on particle swarm optimization [PDF]
Mechanical SciencesAiming at the difficult problem of comprehensive scale design of the six-bar mechanism in engineering practice, kinematic and dynamic analysis and modeling of the Watt-II six-bar mechanism were carried out and combined with the particle swarm ...
H. Ye +13 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The mechanical characteristics analysis of the telescopic wing with adaptive driving mechanism
Advances in Mechanical EngineeringThe deflection of the high aspect ratio telescopic wing is inevitable under aerodynamic force. It is of great significance to ensure that the internal mechanism can exercise smoothly in the deformation state.
Chunfeng Li +5 more
doaj +1 more source
Improved geneva mechanism [PDF]
, 1974 Locking disk (flange) is stepped and lug is added to each arm of star wheel. These changes allow much longer cutout in star wheel stations, essentially eliminating chatter and wear.
Debenham, C. H.
core +1 more source
Sliding Singlet Mechanism Revisited
, 2003 We show that the unification of the doublet Higgs in the standard model (SM) and the Higgs to break the grand unified theory (GUT) group stabilizes the sliding singlet mechanism which can solve the doublet-triplet (DT) splitting problem.
A. Anselm +43 more
core +1 more source