Results 71 to 80 of about 11,555,627 (307)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Pre-Tensioned Flexible Skins for Large-Folding-Ratio UAV Wings: Theory and Tests

open access: yesAerospace
This paper proposes a hybrid rigid–flexible wing design that enables large-area folding and reconfiguration. Based on elasticity theory and fabric constitutive equations, a surface-outward mechanical model incorporating mesoscale weave structures was ...
Guang Yang   +4 more
doaj   +1 more source

Recent Ground Subsidence in the North China Plain, China, Revealed by Sentinel-1A Datasets

open access: yesRemote Sensing, 2020
Groundwater resources have been exploited and utilized on a large scale in the North China Plain (NCP) since the 1970s. As a result of extensive groundwater depletion, the NCP has experienced significant land subsidence, which threatens geological ...
Min Shi   +5 more
doaj   +1 more source

Seesaw induced Higgs Mechanism

open access: yes, 2002
We discuss a two scalar doublets model which induces the Higgs mechanism by means of a seesaw mechanism. This model naturally predicts a light Higgs scalar whose mass is suppressed by the grand unification scale.
Calmet, X.
core   +1 more source

Mechanism Design via Correlation Gap [PDF]

open access: yes, 2010
For revenue and welfare maximization in single-dimensional Bayesian settings, Chawla et al. (STOC10) recently showed that sequential posted-price mechanisms (SPMs), though simple in form, can perform surprisingly well compared to the optimal mechanisms ...
Yan, Qiqi
core   +2 more sources

Moral Mechanisms [PDF]

open access: yesPhilosophy & Technology, 2014
As highly intelligent autonomous robots are gradually introduced into the home and workplace, ensuring public safety becomes extremely important. Given that such machines will learn from interactions with their environment, standard safety engineering methodologies may not be applicable.
openaire   +4 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Omentin-1 effects on mesenchymal stem cells: proliferation, apoptosis, and angiogenesis in vitro

open access: yesStem Cell Research & Therapy, 2017
Background Mesenchymal stem cells (MSCs) are emerging as an extremely promising therapeutic agent for tissue repair. However, limitations exist such as the low numbers of MSCs obtained from donors, and the poor survival and function of donor cells ...
Li Yin   +6 more
doaj   +1 more source

Latching mechanism Patent [PDF]

open access: yes, 1971
Latch for fastening spacecraft docking ...
Cobin, J. C., Rhodes, L. L.
core   +1 more source

Instant preheating mechanism and UHECR [PDF]

open access: yes, 2004
Top-down models assume that the still unexplained Ultra High Energy Cosmic Rays (UHECR's) are the decay products of superheavy particles. Such particles may have been produced by one of the post-inflationary reheating mechanisms and may account for a ...
A. Barrau   +39 more
core   +1 more source

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