Results 181 to 190 of about 10,501,738 (419)
Shedding light on the cell biology of extracellular vesicles
Nature reviews. Molecular cell biology, 2018 G. Niel, G. D’angelo, G. Raposo
semanticscholar +1 more source
Experimental evolution and proximate mechanisms in biology
Synthetic and Systems Biotechnology, 2017 Biological functions - studied by molecular, systems and behavioral biology - are referred to as proximate mechanisms. Why and how they have emerged from the course of evolution are referred to as ultimate mechanisms. Despite the conceptual and technical schism between the disciplines that focus on each, studies from one side can benefit the other ...
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Molecular Oncology, EarlyView.Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad +13 more
wiley +1 more source
Vascular biology in uremia: insights into novel mechanisms of vascular injury [PDF]
, 2004 Ziyad Al‐Aly, John C. Edwards
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EDITORIAL: MECHANICS IN BIOLOGY [PDF]
The ANZIAM Journal, 2018 J. Edward F. Green, Rosemary J. Dyson
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Molecular Oncology, EarlyView.The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang +3 more
wiley +1 more source
Cancer biology: mechanism of antitumour action of vorinostat (suberoylanilide hydroxamic acid), a novel histone deacetylase inhibitor [PDF]
, 2006 Victoria M. Richon
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Molecular Oncology, EarlyView.Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou +11 more
wiley +1 more source
Mean-Independent Noise Control of Cell Fates via Intermediate States
iScience, 2018 Summary: Stochasticity affects accurate signal detection and robust generation of correct cell fates. Although many known regulatory mechanisms may reduce fluctuations in signals, most simultaneously influence their mean dynamics, leading to unfaithful ...
Christopher Rackauckas +2 more
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