Results 201 to 210 of about 2,474,961 (353)

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Rab5c promotes RSV and ADV replication by autophagy in respiratory epithelial cells

Virus Research
Respiratory system diseases caused by respiratory viruses are common and exert tremendous pressure on global healthcare system. In our previous studies, we found that Long non-coding RNA NRAV (Lnc NRAV) and its target molecule Rab5c plays a significant ...
Xiuli Wang, Jing Cheng, Linchao Shen, Meixi Chen, Keran Sun, Jian Li, Miao Li, Cuiqing Ma, Lin Wei   +8 more
doaj  

2P-156 Chemoattractant Sensing Mechanisms in Sperm : Experimental and Simulation Study(Cell biology,The 47th Annual Meeting of the Biophysical Society of Japan)

, 2009
Daisuke Miyashiro, Kogiku Siba, Sinji Kamimura, Syouji Baba, Manabu Yoshida   +4 more
openalex   +2 more sources

Using a systems biology approach to understand and study the mechanisms of metastasis [PDF]

, 2013
Ngoc‐Han Ha, Kent W. Hunter
openalex   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

A back-up mechanism for replication. [PDF]

Elife
Charbon G, Løbner-Olesen A.
europepmc   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Precision psychiatry roadmap: towards a biology-informed framework for mental disorders. [PDF]

Mol Psychiatry
Kas MJH, Penninx BWJH, Knudsen GM, Cuthbert B, Falkai P, Sachs GS, Ressler KJ, Bałkowiec-Iskra E, Butlen-Ducuing F, Leboyer M, Marston H, Luthman J, Mantua V.   +12 more
europepmc   +1 more source

1P223 1C1340 Mechanism of Lyn kinase recruitment to the IgE receptor cluster : dual-color single-molecule tracking study(Cell biology,Oral Presentations,The 48th Annual Meeting of the Biophysical Society of Japan)

, 2010
Koichiro M. Hirosawa, Kenichi Suzuki, Takahiro Fujiwara, Miyako Yahara, Ankita Chadda, Akihiro Kusumi   +5 more
openalex   +2 more sources

A systems biology strategy to identify molecular mechanisms of action and protein indicators of traumatic brain injury [PDF]

, 2014
Chenggang Yu, Angela M. Boutté, Xueping Yu, Bhaskar Dutta, Jacob Feala, Kara Schmid, Jitendra R. Dave, Gregory J. Tawa, Anders Wallqvist, Jaques Reifman   +9 more
openalex   +1 more source