Results 221 to 230 of about 2,474,961 (353)
Correction: Gut microbiota affects PD-L1 therapy and its mechanism in melanoma. [PDF]
Liu S, Liu J, Mei Y, Zhang W.
europepmc +1 more source
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
A multimodal transformer-based visual question answering method integrating local and global information. [PDF]
Huang C, Hu Z.
europepmc +1 more source
Elucidating Mechanisms of Toxicity Using Phenotypic Data from Primary Human Cell Systems—A Chemical Biology Approach for Thrombosis-Related Side Effects [PDF]
Ellen L. Berg+4 more
openalex +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
The neonatal Fc receptor (FcRn): Guardian or Trojan Horse in viral infection? [PDF]
Na L, Zheng Y, Yang JB, Bao HL, Tang YD.
europepmc +1 more source
Deciphering the pharmacological mechanism of the Chinese formula Huanglian-Jie-Du decoction in the treatment of ischemic stroke using a systems biology-based strategy [PDF]
Yanqiong Zhang+7 more
openalex +1 more source