Results 241 to 250 of about 10,501,738 (419)

A fungal effector hijacks a plastid protein to dampen plant immunity; PR1 is here for rescue. [PDF]

Stress Biol
Khan MSS, Islam F, Chen H, Chen J.
europepmc   +1 more source

Peripheral Nerve Regeneration: Mechanism, Cell Biology, and Therapies [PDF]

, 2014

core   +1 more source

S09A5 Single-molecule experiments of F1-ATPase correlating with the crystal structures and molecular simulation(Mechanism of F_1-ATPase Molecular Motor-A Cross Talk among Single Molecule, Structural Biology, and Molecular Simulation Studies-)

, 2007
Hiroyuki Noji
openalex   +2 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Vascular biology: New mechanisms and pathways [PDF]

Vascular Pharmacology, 2016
Dulak, J, Alexander, MY, Randi, AM
openaire   +5 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Epichaperomes: redefining chaperone biology and therapeutic strategies in complex diseases. [PDF]

RSC Chem Biol
Pasala C, Digwal CS, Sharma S, Wang S, Bubula A, Chiosis G.   +5 more
europepmc   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Computational mechanism underlying switching of motor actions. [PDF]

PLoS Comput Biol
Zhong S, Pouratian N, Christopoulos V.
europepmc   +1 more source

Modeling of the Bacterial Mechanism of Methicillin-Resistance by a Systems Biology Approach

, 2009
Ida Autiero, Susan Costantini, Giovanni Colonna   +2 more
openalex   +2 more sources