Results 241 to 250 of about 2,453,415 (302)

Molecular mechanism of human α_1A-adrenoceptor inhibition by Mamba snake toxin AdTx1. [PDF]

Commun Biol
Shi M, Zhang S, Zhu A, Toyoda Y, Kong F, Sun X, Xu X, Yan C, Liu X.   +8 more
europepmc   +1 more source

Collagen Fibrillogenesis: A Mechanism of Structural Biology

Journal of Investigative Dermatology, 1986
openaire   +3 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Target agnostic cellular screening in the era of chemically induced proximity. [PDF]

RSC Med Chem
Jin M.
europepmc   +1 more source

SensRORing cholesterol to drive protumoral myelopoiesis

Molecular Oncology, EarlyView.
Bleve et al. uncover a cholesterol‐driven immune evasion pathway, where RORγ‐dependent myelopoiesis shapes tumor immunosuppression. Targeting RORγ and PCSK9 emerges as a strategy to boost cancer immunotherapy. Protumoral myelopoiesis is a determinant of immunoevasion and tumor spread in many malignancies.
Sara Gennari, Luigi Nezi, Teresa Manzo
wiley   +1 more source

Correction for Yuan et al., Molecular mechanism and functional significance of Wapl interaction with the Cohesin complex. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Correction: Gut microbiota affects PD-L1 therapy and its mechanism in melanoma. [PDF]

Cancer Immunol Immunother
Liu S, Liu J, Mei Y, Zhang W.
europepmc   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

<i>SLC7A11</i>-mediated cell death mechanism in cancer: a comparative study of disulfidptosis and ferroptosis. [PDF]

Front Cell Dev Biol
Zhu WW, Liu Y, Yu Z, Wang HQ.
europepmc   +1 more source