Editorial: Ferroptosis and regulation mechanism in the tumor immune microenvironment for tumor progression and treatment. [PDF]
Wei Y, Pan J, Wang L, Pan Y.
europepmc +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Enarodustat suppresses thymic stromal lymphopoietin expression via hypoxia-inducible factor-mediated c-Jun N-terminal kinases dephosphorylation. [PDF]
Segawa R +3 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Taurine Attenuates M1 Macrophage Polarization and IL-1β Production by Suppressing the JAK1/2-STAT1 Pathway via Metabolic Reprogramming. [PDF]
Zhang Z +11 more
europepmc +1 more source
Small silencing RNA Biology and Mechanism
openaire +1 more source
White spot syndrome virus IE1 protein hijacks the host pentose phosphate pathway to fuel viral replication. [PDF]
Zhang J +5 more
europepmc +1 more source
Biomolecular Condensates in Disease: Decoding the Material State and Engineering Precision Modulators. [PDF]
Han B, Li B, Wang X, Wang L.
europepmc +1 more source
A biological blind spot in addiction research: hormonal contraceptives and adolescent reward seeking. [PDF]
Seemiller LR, Crowley NA.
europepmc +1 more source

