Results 251 to 260 of about 10,501,738 (419)

The roles and applications of extracellular vesicles in cancer

Molecular Oncology, EarlyView.
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley   +1 more source

Computational biology approach to predict molecular mechanism in cancer

Oral Oncology Reports
The field of biology offers a complete structure for studying intricate molecular interactions and the strength of bonding between molecules but with an emphasis on developing treatments and discovering markers in medicine research that hold promise for ...
Ansari Vikhar Danish Ahmad, Subur W. Khan, Qazi Yasar, Mohd Sayeed Shaikh, Mohd Mukhtar Khan   +4 more
doaj  

Computational network biology analysis revealed COVID-19 severity markers: Molecular interplay between HLA-II with CIITA. [PDF]

PLoS One
Park H, Miyano S.
europepmc   +1 more source

2P-156 Chemoattractant Sensing Mechanisms in Sperm : Experimental and Simulation Study(Cell biology,The 47th Annual Meeting of the Biophysical Society of Japan)

, 2009
Daisuke Miyashiro, Kogiku Siba, Sinji Kamimura, Syouji Baba, Manabu Yoshida   +4 more
openalex   +2 more sources

Using a systems biology approach to understand and study the mechanisms of metastasis [PDF]

, 2013
Ngoc‐Han Ha, Kent W. Hunter
openalex   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Therapeutic potential of alternative splicing in cardiovascular diseases

EBioMedicine
Summary: RNA splicing is an important RNA processing step required by multiexon protein-coding mRNAs and some noncoding RNAs. Precise RNA splicing is required for maintaining gene and cell function; however, mis-spliced RNA transcripts can lead to loss ...
Jun Cao, Ziyu Wei, Yu Nie, Hou-Zao Chen
doaj  

Kinetic modelling reveals the presence of multistability in normal and stressful conditions in translational initiation mechanism. [PDF]

PLoS One
Harika GL, Sriram K.
europepmc   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Does experience matter? Understanding the mechanism of the volume-outcome relationship: Learning-by-doing or economies of scale. [PDF]

PLoS One
Maharaj R.
europepmc   +1 more source