Results 291 to 300 of about 10,501,738 (419)

The radical-pair mechanism as a paradigm for the emerging science of quantum biology [PDF]

, 2015
I. K. Kominis
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

MicroRNAs: discovery, breakthrough, and innovation

Blood Science
Jia Yu, Fang Wang
doaj   +1 more source

Bending and Scission: When the Membraneless Condensates Meet Endosome Membrane. [PDF]

MedComm (2020)
Zhang Z, Xie F, Zhang L.
europepmc   +1 more source

Synergy between molecular biology and imaging science toward mechanism-based biomarkers associated with prostate cancer

, 2012
Belinda Seto
openalex   +2 more sources

Features of Knowledge Building in Biology: Understanding Undergraduate Students’ Ideas about Molecular Mechanisms [PDF]

, 2016
Katelyn M. Southard, Tyler Wince, Shanice Meddleton, Molly Bolger   +3 more
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Drug target affinity prediction based on multi-scale gated power graph and multi-head linear attention mechanism. [PDF]

PLoS One
Hu S, Hu J, Zhang X, Jin S, Xu X.
europepmc   +1 more source

1G1510 Mechanisms of signal transduction activated by heavy-ion microbeam induced bystander responses(Cell Biology I,Oral Presentation,The 50th Annual Meeting of the Biophysical Society of Japan)

, 2012
Masanori Tomita, Hideki Matsumoto, Tomoo Funayama, Yuichiro Yokota, Kensuke Otsuka, Munetoshi Maeda, Yasuhiko Kobayashi   +6 more
openalex   +2 more sources

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source