Results 321 to 330 of about 10,501,738 (419)

2SAA-05 Mechanisms of protein and lipid transport in yeast mitochondria(2SAA Mitochondrial neo-biology explored from a membrane dynamics,Symposium,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

, 2014
Toshiya Endo
openalex   +2 more sources

A potential tumor suppressor role of PLK2 in glioblastoma

FEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia, Peirui Wang, Hua Xiao, Qishan Ran, Yan Li, Shengtao Yao   +5 more
wiley   +1 more source

Voluntarily wheel running protects doxorubicin-induced kidney injury by inhibiting oxidative stress through mitochondrial function. [PDF]

PLoS One
Jiang X, Wang Z, Wang L, Wang Y, Zhao L, Jiang H.   +5 more
europepmc   +1 more source

Anthropogenic Mechanisms in Bio- Morphological Evolution A case study of Öset & Rynningeviken Evolutionary Biology

, 2014
Bwanika Daniel
openalex   +2 more sources

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

Diffusible Signal Factors and <i>Xylella fastidiosa</i>: A Crucial Mechanism Yet to Be Revealed. [PDF]

Biology (Basel)
Portaccio L, Vergine M, De Pascali M, De Bellis L, Luvisi A.   +4 more
europepmc   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Editorial: Multi-omics studies on aging and age-related diseases

Frontiers in Cell and Developmental Biology
He-Ping Wang, Nathan Basisty, Jia-Hua Qu, Xiaoman Wang   +3 more
doaj   +1 more source

The systemic evolutionary theory of the origin of cancer (SETOC): an update. [PDF]

Mol Med
Mazzocca A, Ferraro G, Misciagna G.
europepmc   +1 more source

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

FEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang, Kaien Hu, Zhaohui Fang, Sihai Wang, Jie Chen, Dengke Yin, Caiyun Zhang, Gefei Ma   +7 more
wiley   +1 more source