Results 141 to 150 of about 1,837,363 (266)

Deep mechanism design: Learning social and economic policies for human benefit. [PDF]

Proc Natl Acad Sci U S A
Tacchetti A, Koster R, Balaguer J, Leqi L, Pislar M, Botvinick MM, Tuyls K, Parkes DC, Summerfield C.   +8 more
europepmc   +1 more source

Algorithmic Mechanism Design of Evolutionary Computation. [PDF]

Comput Intell Neurosci, 2015
Pei Y.
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Photo(electro)catalytic Water Splitting for Hydrogen Production: Mechanism, Design, Optimization, and Economy. [PDF]

Molecules
Li X, Zhang C, Geng J, Zong S, Wang P.
europepmc   +1 more source

Micro Structure of Injection Molding Machine Mold Clamping Mechanism: Design and Motion Simulation. [PDF]

CAAI Trans Intell Technol, 2017
Zhang Y, Wang X, Williams J, Huang Z, Falkner D, Zhou G, Yang Y, Dong L, Jin Z, Zhuang J, Wang Z, Liu Z.   +11 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

A review of wrist mechanism design and the application in gastrointestinal minimally invasive surgery of multi-degree-of-freedom surgical laparoscopic instruments. [PDF]

Surg Endosc
Tu Y, Jiang J, Huang J, Sui J, Yang S.
europepmc   +1 more source

Pricing Mechanism Design for Centralized Pollutant Treatment with SME Alliances. [PDF]

Int J Environ Res Public Health, 2016
Li Y, Huang B, Tao F.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Current Total Knee Designs: Does Baseplate Roughness or Locking Mechanism Design Affect Polyethylene Backside Wear? [PDF]

Clin Orthop Relat Res, 2017
Sisko ZW, Teeter MG, Lanting BA, Howard JL, McCalden RW, Naudie DD, MacDonald SJ, Vasarhelyi EM.   +7 more
europepmc   +1 more source