Results 171 to 180 of about 4,576,095 (337)

Efficient Path Planning and Truthful Incentive Mechanism Design for Mobile Crowdsensing. [PDF]

Sensors (Basel), 2018
Tao X, Song W.
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Climbing Mechanism Design and Fuzzy PID-Based Control for a Stay Cable De-Icing Robot. [PDF]

Sensors (Basel)
Pei Y, Li S, Chen Z, Xiao H, Huang S, Li C, Xi L.   +6 more
europepmc   +1 more source

Mechanism design of incentive-based reverse auctions with loss-averse 3PLs under incomplete attributes. [PDF]

PLoS One, 2018
Qian X, Huang M, Zhang Q, Zhang Q, Yin M, Wang X.   +5 more
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Deep mechanism design: Learning social and economic policies for human benefit. [PDF]

Proc Natl Acad Sci U S A
Tacchetti A, Koster R, Balaguer J, Leqi L, Pislar M, Botvinick MM, Tuyls K, Parkes DC, Summerfield C.   +8 more
europepmc   +1 more source

Algorithmic Mechanism Design of Evolutionary Computation. [PDF]

Comput Intell Neurosci, 2015
Pei Y.
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Photo(electro)catalytic Water Splitting for Hydrogen Production: Mechanism, Design, Optimization, and Economy. [PDF]

Molecules
Li X, Zhang C, Geng J, Zong S, Wang P.
europepmc   +1 more source

Micro Structure of Injection Molding Machine Mold Clamping Mechanism: Design and Motion Simulation. [PDF]

CAAI Trans Intell Technol, 2017
Zhang Y, Wang X, Williams J, Huang Z, Falkner D, Zhou G, Yang Y, Dong L, Jin Z, Zhuang J, Wang Z, Liu Z.   +11 more
europepmc   +1 more source