Results 51 to 60 of about 13,763,508 (305)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

An sEMG Denoising Method with Improved Threshold Estimation for Rapid Keystroke Tasks

Sensors
Surface electromyography (sEMG) signals are inevitably affected by noise during acquisition, thereby degrading signal quality and analytical reliability.
Pengze Han, Baihui Ding, Penghao Deng, Dengxiong Wu, Huilong Li   +4 more
doaj   +1 more source

Identification and Adjustment of Guide Rail Geometric Errors Based on BP Neural Network

Measurement Science Review, 2017
The relative positions between the four slide blocks vary with the movement of the table due to the geometric errors of the guide rail. Consequently, the additional load on the slide blocks is increased.
He Gaiyun, Huang Can, Guo Longzhen, Sun Guangming, Zhang Dawei   +4 more
doaj   +1 more source

Dynamics Modeling and Analysis of an Underwater Glider with Dual-Eccentric Attitude Regulating Mechanism Using Dual Quaternions

Journal of Marine Science and Engineering, 2022
The underwater glider has difficulty accessing the complex and narrow hadal trench for observation, which is affected by its limited regulation capability of pitch angle (−45°~45°).
Peng Wang, Xuehao Wang, Yanhui Wang, Wendong Niu, Shaoqiong Yang, Chao Sun, Chenyi Luo   +6 more
doaj   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Mechanism design for eliciting probabilistic estimates from multiple suppliers with unknown costs and limited precision [PDF]

, 2009
This paper reports on the design of a novel two-stage mechanism, based on strictly proper scoring rules, that allows a centre to acquire a costly probabilistic estimate of some unknown parameter, by eliciting and fusing estimates from multiple suppliers.
Enrico H. Gerding, Jennings, N. R., Papakonstantinou, Athanasios, Alex Rogers, Nicholas R. Jennings, Gerding, E. H, Athanasios Papakonstantinou, Rogers, Alex, Gerding, Enrico, Jennings, Nicholas, Papakonstantinou, A., Rogers, A.   +11 more
core   +2 more sources

Mechanism Design and Blockchains

CoRR, 2020
Game theory is often used as a tool to analyze decentralized systems and their properties, in particular, blockchains. In this note, we take the opposite view. We argue that blockchains can and should be used to implement economic mechanisms because they can help to overcome problems that occur if trust in the mechanism designer cannot be assumed ...
Akaki Mamageishvili, Jan Christoph Schlegel   +1 more
openaire   +2 more sources

Nature and role of intermediate representation (IR) in the design process [PDF]

, 2005
This paper aims to show the key role of the intermediate representations (IR) in the design process and especially in the car design process. For a better understanding of the concept of design, which is by nature conceptual, we propose to study the ...
AOUSSAT, Améziane, BOUCHARD, Carole, CAMOUS, Roger   +2 more
core  

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Reinforcement mechanism design [PDF]

Proceedings of the Twenty-Sixth International Joint Conference on Artificial Intelligence, 2017
We put forward a modeling and algorithmic framework to design and optimize mechanisms in dynamic industrial environments where a designer can make use of the data generated in the process to automatically improve future design. Our solution, coined reinforcement mechanism design, is rooted in game theory but incorporates recent AI techniques to get rid
openaire   +2 more sources