Results 181 to 190 of about 1,539,032 (313)

The mechanism of cloud loss phenomena in orange juice

, 1974
The importance of many factors for the cloud stability of orange juice was investigated. By the determination of methanol, cloud loss of orange juice could be ascribed directly to the action of pectin esterase.
Krop, J.J.P.
core  

Study on the Mechanism of Action of Baicalein in Inhibiting the Invasion of <i>Streptococcus agalactiae</i>. [PDF]

Antioxidants (Basel)
Jiang L, He X, Wang Y, Liu Y, Li X, Xu F.   +5 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Exploration of the Mechanism of Action of Dendrobium officinale in the Treatment of Liver Cancer Based on Network Pharmacology, Molecular Docking and in vitro Validation

Journal of Hepatocellular Carcinoma
Shuimeng Zhan,1,&ast; Xinyan Lu,1,&ast; Hongyan Guo,1 Yang Liu,1 Zhi Li,1 Wei Xu,2 Fang Xia,2 Huanjun Tang,2 Yi Tian,2 Jing Chen,3 Xuan Lin1 1Department of Endocrinology, CR & WISCO General Hospital Affiliated to Wuhan University of Science ...
Zhan S, Lu X, Guo H, Liu Y, Li Z, Xu W, Xia F, Tang H, Tian Y, Chen J, Lin X   +10 more
doaj  

A behavioral integration mechanism underlies action timing. [PDF]

Sci Adv
Strassmann P, Cai X, Zhang B, Howard CD, Cook J, Jin X.   +5 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

“Illuminating” Echinocandins’ Mechanism of Action

ACS Central Science, 2020
Boon Shing Loh, Wee Han Ang
doaj   +1 more source

Transarterial Embolization in Osteoarthritis of the Knee: Mechanism of Action and Current Results. [PDF]

Dtsch Arztebl Int
Collettini F, Fleckenstein FN, Winkler T, Wirtz DC, Perka C, Gebauer B.   +5 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Integrated omics reveal a unique antibacterial mechanism of action for the small molecule HSI#6. [PDF]

Curr Res Microb Sci
Sedky H, Hamed MB, Vermeire K, Schymkowitz J, Karamanou S, Economou A.   +5 more
europepmc   +1 more source