Results 11 to 20 of about 1,944 (169)

RNA-binding proteins orchestrating immunity in plants. [PDF]

Plant J
SUMMARY RNA‐binding proteins (RBPs) direct the function and fate of RNA throughout the RNA lifecycle and play important roles in plant immunity, orchestrating the post‐transcriptional reprogramming of the transcriptome following induction of plant immune responses, a process that we term ‘RBP‐mediated immunity’. Although the importance of specific RBPs
Bach-Pages M, Menon A, Wadley B, Castello A, Preston GM.   +4 more
europepmc   +2 more sources

Engineering microalgae for water phosphorus recovery to close the phosphorus cycle. [PDF]

Plant Biotechnol J, 2023
Summary As a finite and non‐renewable resource, phosphorus (P) is essential to all life and crucial for crop growth and food production. The boosted agricultural use and associated loss of P to the aquatic environment are increasing environmental pollution, harming ecosystems, and threatening future global food security.
Wang L, Jia X, Xu L, Yu J, Ren S, Yang Y, Wang K, López-Arredondo D, Herrera-Estrella L, Lambers H, Yi K.   +10 more
europepmc   +2 more sources

Platelet response to influenza vaccination reflects effects of aging. [PDF]

Aging Cell, 2023
Platelets mediate innate immune responses as well as thrombosis. We found an age‐associated increase in platelet activation RNAs, further increased in skilled nursing facility (enriched for frailty) vs. community‐dwelling (largely non‐frail) older adults. Tensor decomposition analysis revealed distinct trajectories of platelet activation following high‐
Konstorum A, Mohanty S, Zhao Y, Melillo A, Vander Wyk B, Nelson A, Tsang S, Blevins TP, Belshe RB, Chawla DG, Rondina MT, Gill TM, Montgomery RR, Allore HG, Kleinstein SH, Shaw AC.   +15 more
europepmc   +2 more sources

Emerging Roles of Macrophage Polarization in Osteoarthritis: Mechanisms and Therapeutic Strategies. [PDF]

Orthop Surg
Macrophages are key players in osteoarthritis (OA) pathology. In this review, we focus on synovial macrophages, adipose tissue macrophages, and osteoclasts, to investigate their roles in the development of OA. We review recent key findings related to macrophage polarization and OA, including pathogenesis, molecular pathways, and novel therapeutics ...
Yuan Z, Jiang D, Yang M, Tao J, Hu X, Yang X, Zeng Y.   +6 more
europepmc   +2 more sources

Quantifying effects of cold acclimation and delayed springtime photosynthesis resumption in northern ecosystems

New Phytologist, Volume 240, Issue 3, Page 984-1002, November 2023., 2023
Summary Land carbon dynamics in temperate and boreal ecosystems are sensitive to environmental change. Accurately simulating gross primary productivity (GPP) and its seasonality is key for reliable carbon cycle projections. However, significant biases have been found in early spring GPP simulations of northern forests, where observations often suggest ...
Yunpeng Luo, Arthur Gessler, Petra D'Odorico, Koen Hufkens, Benjamin D. Stocker   +4 more
wiley   +1 more source

Pyroptosis in platelets: Thrombocytopenia and inflammation

Journal of Clinical Laboratory Analysis, Volume 37, Issue 4, February 2023., 2023
This review describes the complex mechanisms of pyroptosis in platelets and their relative diseases. Platelet NLRP3 activation is induced via LPS, HMGB1 and S100A8/A9 receptor TLR4, collagen receptor GPVI, and thrombin. Upon NLRP3 activation, NLRP3 forms inflammasome complexes with the ASC and pro‐caspase‐1 that regulate the production of ...
Yang Su, Tiannan Zhang, Rui Qiao
wiley   +1 more source

Improvement of Soybean Crop for Yield, Stress Tolerance, and Value‐Added Products Using a Transgenic Approach

Advances in Agriculture, Volume 2023, Issue 1, 2023., 2023
Soybean (Glycine max) is an economically important crop, ranking first among the edible oilseed crops in the world due to its oil content and nutritional value. Besides, it is used as a dietary supplement and a source of pharmaceuticals. The recent rapid climate changes and increasing global population have led to increasing demand for vegetable oil ...
Deepak B. Shelke, Mahadev R. Chambhare, Ganesh C. Nikalje, T. D. Nikam, Vikas Srivastava   +4 more
wiley   +1 more source

Molecular mechanisms and therapeutic target of NETosis in diseases

MedComm, Volume 3, Issue 3, September 2022., 2022
NETs are involved in the pathogenesis and progression of various diseases, such as sepsis, SLE, RA, SVV, IBD, cancer, and COVID‐19. Components of NETs may act as autoantigens, leading to inflammation and autoimmune diseases. In addition, some diseases aggravate NETosis and cause a vicious circle. Abstract Evidence shows that neutrophils can protect the
Jiayu Huang, Weiqi Hong, Meihua Wan, Limin Zheng   +3 more
wiley   +1 more source

TetraFLEX: Design and kinematic analysis of a novel self‐aligning family of 3T1R parallel manipulators

Journal of Field Robotics, Volume 39, Issue 5, Page 617-630, August 2022., 2022
Abstract A new family of 3T1R parallel manipulators (PMs) with self‐aligning property, named TetraFLEX, is presented. 3T1R manipulators have many applications in different fields. Moreover, self‐aligning property refers to the presence of passive joints in the PM limbs that are conceived to compensate for possible misalignments between the sliding ...
Henrique Simas, Raffaele Di Gregorio, Roberto Simoni   +2 more
wiley   +1 more source

Inflammasomes in neuroinflammatory and neurodegenerative diseases [PDF]

, 2019
Neuroinflammation and neurodegeneration often result from the aberrant deposition of aggregated host proteins, including amyloid-beta, alpha-synuclein, and prions, that can activate inflammasomes.
Lamkanfi, Mohamed, Srinivasan, Sahana, van Loo, Geert, Voet, Sofie   +3 more
core   +2 more sources