Results 51 to 60 of about 4,082,729 (264)

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak   +9 more
wiley   +1 more source

Letter to the editor: Neutralizing antibodies for the treatment of COVID-19

open access: yesActa Pharmaceutica Sinica B, 2021
Zeqi Zhou   +4 more
doaj   +1 more source

Exploratory Study on the Impact of Intestinal Fungi on the Progression of Heart Failure in Patients with Chronic Kidney Disease

open access: yesXiehe Yixue Zazhi
ObjectiveTo investigate the role of intestinal fungi in the progression of heart failure (HF) associated with chronic kidney disease (CKD).MethodsThis study consisted of two parts. The first part was a clinical study. Fecal samples from CKD patients (CKD
LI Shuting   +4 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono   +7 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Multifunctional Graphene–Concrete Composites: Performance and Mechanisms

open access: yesApplied Sciences
Concrete is a cornerstone material in the construction industry owing to its versatile performance; however, its inherent brittleness, low tensile strength, and poor permeability resistance limit its broader application.
Jun Shang   +7 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Behavioral Study of Dashboard Mechanisms

open access: yes
Visualization dashboards are increasingly used in strategic settings like auctions to enhance decision-making and reduce strategic confusion. This paper presents behavioral experiments evaluating how different dashboard designs affect bid optimization in reverse first-price auctions.
Paula Kayongo   +2 more
openaire   +3 more sources

STUDIES ON THE MECHANISM OF THE PAROXYSMAL TACHYCARDIA

open access: yesNihon Naika Gakkai Zasshi, 1973
従来より,発作性頻拍症は精神的緊張により惹起されやすい事は良く知られた事実であるが,その真の発生機序については現在のところ明らかにされていない.それ故に,神経性因子,とくに交感神経緊張状態が発作性頻拍症の発生,および,その維持機構に,如何なる影響を及ぼすかについて検討した.まず発作性頻拍症の患者の大部分が交感神経緊張状態に頻拍発作が起こりやすい事実より, epinephrine (6γ/kg)の筋注による誘発試験を20例の発作性上室性頻拍症の既往を有する患者に試みたところ,11例に頻拍発作を誘発し得た.臨床例,また実験結果でも心房性および心室性期外収縮がtriggerとなつて発作性頻拍が発生する事より,発作性頻拍症の発生には,1)発作性頻拍の発生のtriggerとなる期外収縮が惹起する事,2 ...
openaire   +3 more sources

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