Results 41 to 50 of about 169,186,284 (259)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Theoretical basis of comparison of models of public administration [PDF]

, 2013
In connection to the process of the public administration reforms which take place in most of the European countries and also in connection to the "European administrative space", the issues of studying and mutually comparing administrative systems of ...
Čechák, Vladimír
core   +1 more source

Theoretical foundations of interaction between public administration bodies and civil society institutions

Theory and Practice of Public Administration
This article examines the theoretical foundations of interaction between public administration bodies and civil society institutions in the context of Ukraine’s democratic transformation.
Nadiya Myrna, Oleksandr Stasiuk
doaj   +1 more source

PROBLEMS OF REFORMING THE PROFESSIONAL AND COMMUNICATIVE CULTURE IN THE UKRAINE PUBLIC ADMINISTRATION

Публічне управління та регіональний розвиток, 2018
The contribution of foreign and domestic researchers to the study of problems of professional and communicative culture is analyzed in the article. Considerable attention is paid to the characterization of the specifics of the reform of the professional ...
Mykhaylo Bagmet, Inna Horzhevska, Oksana Malikina   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Citizen Participation in Public Administration: Views from Lebanon

, 2013
This article examines citizen participation in Lebanon. Specifically, we apply the International Association for Public Participation Spectrum of Public Participation (2007) and use survey, interview, and archival data to understand how and why Lebanese ...
Antoun R., Nabatchi T., AbouAssi K.
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Where we stand: A review on equity in public administration and policy

, 2023
Public administration identifies social equity as a foundational pillar of the field; despite many calls to action for research to emphasize equity, only 127 articles across 22 journals (11 Public Administration, 11 Policy) over the past decade (2009 ...
Shen, Ruowen, Curley, Cali, Coleman, Michael, Harrison, Nicole   +3 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source