Results 91 to 100 of about 11,335 (213)

Feed additives for methane mitigation: Modeling the impact of feed additives on enteric methane emission of ruminants—Approaches and recommendations

Journal of Dairy Science
: Over the past decade, there has been considerable attention on mitigating enteric methane (CH4) emissions from ruminants through the utilization of antimethanogenic feed additives (AMFA).
Jan Dijkstra, André Bannink, Guilhermo F.S. Congio, Jennifer L. Ellis, Maguy Eugène, Florencia Garcia, Mutian Niu, Ronaldo E. Vibart, David R. Yáñez-Ruiz, Ermias Kebreab   +9 more
doaj   +1 more source

Mechanistic Modeling of Rotating Algal Biofilms

Biotechnology and Bioengineering
ABSTRACT Biofilm‐based microalgal cultivation systems have emerged as a promising alternative to conventional suspended growth methods, offering improved light utilization and biomass productivity. Among these, Rotating Algal Biofilm (RAB) systems are particularly advantageous by subjecting cells to short periodic light/dark (L/D ...
Gao, Yan, Perré, Patrick, Fierro, Ignacio, Lopes, Filipa, Bernard, Olivier   +4 more
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Climate change may improve physiological suitability for three widespread Mexican snakes

Frontiers in Amphibian and Reptile Science
IntroductionThermal tolerance and performance breadth can define the suitable areas where reptiles can survive and perform at an optimal physiological level.
Ricardo Figueroa-Huitrón, Ricardo Figueroa-Huitrón, Hibraim Adán Pérez-Mendoza   +2 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Ecophysiological constraints outperform environmental predictors in forecasting climate-driven extinction risk of a Cerrado endemic lizard

Frontiers in Amphibian and Reptile Science
IntroductionForecasting species responses to climate change using only environmental predictors may underestimate extinction risk because it ignores physiological constraints.MethodsWe compared species distribution models for Micrablepharus atticolus ...
Vitor H. G. L. Cavalcante, Gabriel H. O. Caetano, Leandro B. Godinho, Barry R. Sinervo, Donald B. Miles, Guarino R. Colli   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Behavioural Procedural Models – a multipurpose mechanistic account [PDF]

The Journal of Philosophical Economics, 2012
In this paper we outline an epistemological defence of what wecall Behavioural Procedural Models (BPMs), which represent the processes of individual decisions that lead to relevant economic patterns as psychologically (rather than rationally) driven ...
Leonardo Ivarola, Gustavo Marqués
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source