Results 91 to 100 of about 869,043 (286)

A software package for immunologists to learn simulation modeling

open access: yesBMC Immunology, 2020
Background As immunology continues to become more quantitative, increasingly sophisticated computational tools are commonly used. One useful toolset are simulation models.
Andreas Handel
doaj   +1 more source

Network properties underlying seed germination control [PDF]

open access: yes, 2007
We sought to gain a mechanistic understanding of the control of seed dormancy and germination by hormone balance. The field has matured to a stage where most of the key genes are known, and competing hypotheses have been proposed to explain how hormone ...
Fozard, John, Penfield, Steven
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

O emprego de lipases como agentes de resolução cinética de enantiômeros em síntese orgânica: aspectos gerais sobre a influência do solvente

open access: yesQuímica Nova, 1999
In organic synthesis, lipases are the most frequently used biocatalysts. They are efficient stereoselective catalysts in the kinetic resolution of a wide variety of chiral compounds.
Costa Valentim Emilio Uberti   +1 more
doaj  

Drug-target identification in COVID-19 disease mechanisms using computational systems biology approaches

open access: yesFrontiers in Immunology
IntroductionThe COVID-19 Disease Map project is a large-scale community effort uniting 277 scientists from 130 Institutions around the globe. We use high-quality, mechanistic content describing SARS-CoV-2-host interactions and develop interoperable ...
Anna Niarakis   +108 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

ESTUDIO COMPARATIVO ENTRE CORRELACIONES EMPÍRICAS Y MODELOS MECANÍSTICOS PARA FLUJO MULTIFÁSICO EN POZOS HORIZONTALES DE INYECCIÓN DE VAPOR

open access: yesRevista Fuentes El Reventón Energético, 2011
he steam injection in horizontal wells has great applicability to heavy oil reservoirs. However, one of the challenges of this technology is the prediction of the profiles of pressure, temperature and vapor quality along the well.
Gustavo Rojas Sosa   +1 more
doaj   +2 more sources

Multi-objective optimization in biotechnological processes: application to plant cell suspension cultures of Thevetia peruviana

open access: yesRevista Facultad de Ingeniería Universidad de Antioquia, 2018
Bioprocesses productivity is a compromise between two conflicting objectives, maximization of biomass growth rate and minimization of substrate consumption.
Adriana Patricia Villegas-Quiceño   +4 more
doaj  

Some Properties of the Speciation Model for Food-Web Structure - Mechanisms for Degree Distributions and Intervality

open access: yes, 2005
We present a mathematical analysis of the speciation model for food-web structure, which had in previous work been shown to yield a good description of empirical data of food-web topology. The degree distributions of the network are derived.
A.G. Rossberg   +35 more
core   +1 more source

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