Results 171 to 180 of about 11,335 (213)
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2009
Abstract The empiric models discussed heretofore have not explicitly incorporated knowledge of specific biological mechanisms, although in some cases, the form of the dose–response model may be motivated by theoretical considerations, such as the linear-quadratic cell-killing model used in radiobiology (see Chapter 6). In some instances,
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Abstract The empiric models discussed heretofore have not explicitly incorporated knowledge of specific biological mechanisms, although in some cases, the form of the dose–response model may be motivated by theoretical considerations, such as the linear-quadratic cell-killing model used in radiobiology (see Chapter 6). In some instances,
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Mechanistic Modeling of Carbonated Waterflooding
SPE Improved Oil Recovery Conference, 2018AbstractCO2 enhanced oil recovery is usually affected by poor sweep efficiency due to unfavorable mobility contrast between the injected CO2 and oil. To alleviate this problem, CO2 is added to the injected brine and transported in the reservoir by flood water.
Alireza Sanaei +2 more
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Mechanistic Model of Wound Contraction
Journal of Surgical Research, 1993The interplay between cellular, biochemical, and biomechanical phenomena which result in wound contraction is examined with the aid of a mathematical model. The model accounts for fibroblasts repopulating the wound extracellular matrix (ECM) by a combination of migration and proliferation and, in the course of exerting traction forces associated with ...
R T, Tranquillo, J D, Murray
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Mechanistic biological modeling thrives
Science, 2016In their Perspective “Systems biology (un)certainties” (23 October 2015, p. [386][1]), P. D. W. Kirk et al. may give readers the impression that mathematical modeling and computer simulations of biological systems have fallen on hard times, owing to difficulties in measuring parameter values.
Ben, O'Shaughnessy, Thomas D, Pollard
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A mechanistic damage model for ligaments
Journal of Biomechanics, 2017The accuracy of biomechanical models is predicated on the realism by which they represent their biomechanical tissues. Unfortunately, most models use phenomenological ligament models that neglect the behaviour in the failure region. Therefore, the purpose of this investigation was to test whether a mechanistic model of ligamentous tissue portrays ...
Jeff M, Barrett, Jack P, Callaghan
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When mechanistic models explain
Synthese, 2006Not all models are explanatory. Some models are data summaries. Some models sketch explanations but leave crucial details unspecified or hidden behind filler terms. Some models are used to conjecture a how-possibly explanation without regard to whether it is a how-actually explanation.
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Mechanistic models are hypotheses: A perspective
Mathematical BiosciencesScience involves perceiving patterns (events that are repeated) in observations, hypothesizing causal explanations (underlying processes), and testing them. Mathematical models either describe or provide explanations for patterns. The equations of descriptive models have convenient mathematical properties while those of mechanistic ones correspond to ...
John W Glasser, Zhilan Feng
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Mechanistic models for wind dispersal
Trends in Plant Science, 2006The growing need for ecological forecasts of, for example, species migration, has increased interest in developing mechanistic models for wind dispersal of seeds, pollen and spores. Analytical models are only able to predict mean dispersal distances, whereas sophisticated trajectory simulation models are able to incorporate rare wind conditions causing
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Mechanistic Modelling and Risk Assessment
Pharmacology & Toxicology, 1993Abstract: Risk Assessment in the United States has been rapidly changing over the last few years. The historical methods and endpoints by which risk estimates were derived are gradually being replaced by newer methods and a broader spectrum of endpoints. For carcinogenic risk assessment, there is movement from the routinely used “linearized multistage
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Mechanistic Modeling of Salmonellosis
Quantitative Microbiology, 2000The serious limitation of the available human data contributes to the need for making simplifying assumptions for dose-response modeling which has led to frequent use of a single function, the beta-Poisson function, as a default dose-response model form. This function is a concave, low-dose linear function.
Margaret E. Coleman, Harry M. Marks
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