Results 191 to 200 of about 22,796,869 (307)

Mechanistic models of humoral kinetics following COVID-19 vaccination. [PDF]

J R Soc Interface
Stocks D, Thomas A, Finn A, Danon L, Brooks-Pollock E.   +4 more
europepmc   +2 more sources

Deep time evolution of the Latitudinal Diversity Gradient: Insights from mechanistic models. [PDF]

PLoS One
Lorcery M, Husson L, Salles T, Lavergne S, Hagen O, Skeels A.   +5 more
europepmc   +1 more source

Biophysical and Mechanistic Models for Disease-Causing Protein Variants.

TIBS -Trends in Biochemical Sciences. Regular ed, 2019
A. Stein, D. Fowler, R. Hartmann-Petersen, K. Lindorff‐Larsen   +3 more
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Mechanistic models position ceritinib as a nuclear integrity disrupting therapy in pediatric liver tumors. [PDF]

J Exp Clin Cancer Res
Demir S, Kessler T, Hotes A, Häberle B, Hiyama E, Hishiki T, Indersie E, Branchereau S, Vokuhl C, Dorel M, Lehrach H, Lange B, Cairo S, Kappler R.   +13 more
europepmc   +1 more source

Developing Performance-Based Mix Design Framework Using Asphalt Mixture Performance Tester and Mechanistic Models. [PDF]

Polymers (Basel), 2023
Lee JS, Lee SY, Le THM.
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Rapid, interpretable data-driven models of neural dynamics using recurrent mechanistic models. [PDF]

Proc Natl Acad Sci U S A
Burghi TB, Ivanova M, Morozova E, Wang H, Marder E, O'Leary T.   +5 more
europepmc   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

The Product neutrality function defining genetic interactions emerges from mechanistic models of cell growth. [PDF]

Elife
Fuentes Valenzuela L, Francois P, Skotheim JM.   +2 more
europepmc   +1 more source