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Mechanistic Modeling of Salmonellosis
Quantitative Microbiology, 2000The serious limitation of the available human data contributes to the need for making simplifying assumptions for dose-response modeling which has led to frequent use of a single function, the beta-Poisson function, as a default dose-response model form. This function is a concave, low-dose linear function.
Margaret E. Coleman, Harry M. Marks
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Mechanistic Modelling and Risk Assessment
Pharmacology & Toxicology, 1993Abstract: Risk Assessment in the United States has been rapidly changing over the last few years. The historical methods and endpoints by which risk estimates were derived are gradually being replaced by newer methods and a broader spectrum of endpoints. For carcinogenic risk assessment, there is movement from the routinely used “linearized multistage
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When mechanistic models explain
Synthese, 2006Not all models are explanatory. Some models are data summaries. Some models sketch explanations but leave crucial details unspecified or hidden behind filler terms. Some models are used to conjecture a how-possibly explanation without regard to whether it is a how-actually explanation.
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A mechanistic approach to delayed coking modelling
2005Abstract The valorisation of oil distillation residues constitutes a major problem for refineries. Thermal processes like visbreaking and delayed coking are still quite diffused technologies. This paper presents some major aspects of the delayed coking kinetic modelling and some preliminary results compared with experimental data.
BOZZANO, GIULIA LUISA, DENTE, MARIO
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Applying Mechanistic Models in Bioprocess Development
2012The available knowledge on the mechanisms of a bioprocess system is central to process analytical technology. In this respect, mechanistic modeling has gained renewed attention, since a mechanistic model can provide an excellent summary of available process knowledge.
Rita, Lencastre Fernandes +6 more
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A Mechanistic Model of Meaning
Biosemiotics, 2010Ever since the scientific revolution, physics has been the ‘queen’ science and biologists have been split into twp opposite camps, one in favour and one against adopting its paradigm, a view that has become known as mechanism. That paradigm, however, has undergone at least three major changes in the last few centuries, and we need to keep them well in ...
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Mechanistic Models of Cognition
2020Abstract Psychological and neuroscientific explanations strongly constrain one another, so much so that psychology has become an integral part of cognitive neuroscience. The functional analyses of classical cognitive psychology can be integrated with neuroscientific explanations to form multilevel mechanistic explanations of cognition ...
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Mechanistic Models and Modeling Disorders
2016Recent debate has focused on how disorders should be modeled, and on how their onset, course and final outcome should be explained. I shall here address some issues arising from modeling neuropsychiatric disorders, which are in many cases still poorly understood, subject to a very high rate of individual variations, and tackled from different ...
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