Results 61 to 70 of about 869,043 (286)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel +3 more
wiley +1 more source
Inference in Nonlinear Differential Equations [PDF]
, 2015 Parameter inference in mechanistic models of coupled differential equations is a challenging problem. We propose a new method using kernel ridge regression in Reproducing Kernel Hilbert Spaces (RKHS). A three-step gradient matching algorithm is developed
Filippone, Maurizio +3 more
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Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report
Pediatric Blood &Cancer, EarlyView.ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan +6 more
wiley +1 more source
Evaluating Artificial Models of Cognition
Studies in Logic, Grammar and Rhetoric, 2015 Artificial models of cognition serve different purposes, and their use determines the way they should be evaluated. There are also models that do not represent any particular biological agents, and there is controversy as to how they should be assessed ...
Miłkowski Marcin
doaj +1 more source
, 1991 Several models and theories are reviewed that incorporate the idea of radiation-induced lesions (repairable and/or irreparable) that can be related to molecular lesions in the DNA molecule. Usually the DNA double-strand or chromatin break is suggested as the critical lesion.
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider +4 more
wiley +1 more source
Review: When worlds collide – poultry modeling in the ‘Big Data’ era
Animal, 2022 Within poultry production systems, models have provided vital decision support, opportunity analysis, and performance optimization capabilities to nutritionists and producers for decades.
E.M. Leishman +8 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman +7 more
wiley +1 more source
IEEE AccessPredicting stochastic spreading processes across large-scale multi-layered networks remains a significant computational challenge due to the intricate interplay between network structure and spread dynamics.
Mohammad Hossein Samaei +2 more
doaj +1 more source
The functional response of metamorphosis rates to climatic variation: A case study with Amblyomma variegatum [PDF]
, 2012 Amblyomma variegatum is a three host hard tick that has demonstrated extensive range expansion over the last 150 years. This _Tropical Bont Tick_ vectors a number of economically important bacterial diseases of ruminants including the pathogen Ehrlichia ...
Guinat, Claire +4 more
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