Results 51 to 60 of about 7,721,638 (300)

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

From large-scale to micro machining: a review of force prediction models [PDF]

, 2013
In this paper, a reviewof work performed in the area of force modelling in metal cutting processes is presented. Past and present trends are described and criticised to compare their relevance with current requirements.
FROMENTIN, Guillaume, GERMAIN, Dimitri, Bissey-Breton, Stephanie, BISSEY BRETON, Stéphanie, POULACHON, Gerard   +4 more
core  

Nonlocal Mechanistic Models in Ecology: Numerical Methods and Parameter Inferences

Applied Sciences, 2023
Animals utilize their surroundings to make decisions on how to navigate and establish their territories. Some species gather information about competing groups by observing them from a distance, detecting scent markings, or relying on memories of ...
Erin Ellefsen, Nancy Rodríguez
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Mechanistic Modeling of Architectural Vulnerability Factor [PDF]

ACM Transactions on Computer Systems, 2015
Reliability to soft errors is a significant design challenge in modern microprocessors owing to an exponential increase in the number of transistors on chip and the reduction in operating voltages with each process generation. Architectural Vulnerability Factor (AVF) modeling using microarchitectural simulators enables architects to make informed ...
Arun Arvind Nair, Stijn Eyerman, Jian Chen, Lizy Kurian John, Lieven Eeckhout   +4 more
openaire   +3 more sources

Mechanistic mathematical models: An underused platform for HPV research [PDF]

, 2017
Health economic modeling has become an invaluable methodology for the design and evaluation of clinical and public health interventions against the human papillomavirus (HPV) and associated diseases. At the same time, relatively little attention has been
Patti E. Gravitt, Marc D. Ryser, Gravitt, Patti, Myers, Evan R., Ryser, Marc, Evan R. Myers   +5 more
core   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Mechanistic Models

, 1991
Several models and theories are reviewed that incorporate the idea of radiation-induced lesions (repairable and/or irreparable) that can be related to molecular lesions in the DNA molecule. Usually the DNA double-strand or chromatin break is suggested as the critical lesion.
openaire   +3 more sources

How to Model Mechanistic Hierarchies [PDF]

Philosophy of Science, 2016
Mechanisms are usually viewed as hierarchical, with lower levels of a mechanism influencing, and decomposing, its higher-level behavior. To draw quantitative predictions from a model of a mechanism, the model must capture this hierarchical aspect. Recursive Bayesian networks (RBNs) were put forward by Lorenzo Casini et al.
openaire   +3 more sources

MEPDG Work Plan Task No. 8: Validation of Pavement Performance Curves for the Mechanistic-Empirical Pavement Design Guide, 2009 [PDF]

, 2009
The objective of this research is to determine whether the nationally calibrated performance models used in the Mechanistic-Empirical Pavement Design Guide (MEPDG) provide a reasonable prediction of actual field performance, and if the desired accuracy ...

core