Results 31 to 40 of about 869,043 (286)

A Method to Identify and Analyze Biological Programs through Automated Reasoning. [PDF]

open access: yes, 2016
Predictive biology is elusive because rigorous, data-constrained, mechanistic models of complex biological systems are difficult to derive and validate.
and Stephen Emmott, 5   +5 more
core   +1 more source

Mechanistic Modelling of Radiation Responses [PDF]

open access: yesCancers, 2019
Radiobiological modelling has been a key part of radiation biology and therapy for many decades, and many aspects of clinical practice are guided by tools such as the linear-quadratic model. However, most of the models in regular clinical use are abstract and empirical, and do not provide significant scope for mechanistic interpretation or making ...
Stephen J. McMahon, Kevin M. Prise
openaire   +3 more sources

A mechanistic model of photosynthesis in microalgae [PDF]

open access: yesBiotechnology and Bioengineering, 2002
AbstractA dynamic model of photosynthesis is developed, accounting for factors such as photoadaptation, photoinhibition, and the “flashing light effect.” The model is shown to explain the reported photosynthesis–irradiance responses observed under various conditions (constant low light, constant intense irradiance, flashing light, diurnal variation in ...
F Camacho, Rubio   +4 more
openaire   +2 more sources

Predictive ability of a process‐based versus a correlative species distribution model

open access: yesEcology and Evolution, 2020
Species distribution modeling is a widely used tool in many branches of ecology and evolution. Evaluations of the transferability of species distribution models—their ability to predict the distribution of species in independent data domains—are, however,
Steven I. Higgins   +4 more
doaj   +1 more source

Unification Strategies in Cognitive Science [PDF]

open access: yes, 2016
Cognitive science is an interdisciplinary conglomerate of various research fields and disciplines, which increases the risk of fragmentation of cognitive theories.
Miłkowski, Marcin
core   +3 more sources

Mechanistic model of hormonal contraception

open access: yesPLOS Computational Biology, 2020
Contraceptive drugs intended for family planning are used by the majority of married or in-union women in almost all regions of the world. The two most prevalent types of hormones associated with contraception are synthetic estrogens and progestins. Hormonal based contraceptives contain a dose of a synthetic progesterone (progestin) or a combination of
A. Armean Wright   +3 more
openaire   +4 more sources

Systems immunology: When systems biology meets immunology

open access: yesFrontiers in Immunology
The immune system is an intricate network of cells, proteins, and signaling pathways that coordinate protective responses and, when dysregulated, drive immune−related diseases.
Lucía Alfonso-González   +3 more
doaj   +1 more source

Bridging Mechanistic and Phenomenological Models of Complex Biological Systems

open access: yes, 2016
The inherent complexity of biological systems gives rise to complicated mechanistic models with a large number of parameters. On the other hand, the collective behavior of these systems can often be characterized by a relatively small number of ...
Qiu, Peng, Transtrum, Mark K.
core   +2 more sources

A Mechanistic Model for Ncd Directionality [PDF]

open access: yesJournal of Biological Chemistry, 2001
Ncd is a kinesin-related protein that drives movement to the minus-end of microtubules. Pre-steady-state kinetic experiments have been employed to investigate the cooperative interactions between the motor domains of the MC1 dimer and to establish the ATPase mechanism.
K A, Foster, A T, Mackey, S P, Gilbert
openaire   +2 more sources

Comparison of Pruning Regimes for Stone Pine (Pinus pinea L.) Using a Functional- Structural Plant Model [PDF]

open access: yes, 2012
Functional-Structural Plant Models (FSPM) are becoming important tools for modeling the structure and growth of plants, including complex organisms like trees.
Almeida Ribeiro, Nuno   +2 more
core   +1 more source

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